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Table 1 The expression of miR-101-3p, and the contents of PGI, PGII and CEA in the serum of patients with atrophic gastritis (AG) and gastric cancer (GC), and healthy volunteers (Normal control)

From: Serum miR-101-3p combined with pepsinogen contributes to the early diagnosis of gastric cancer

Index

Normal control (n = 50)

AG (n = 61)

GC (n = 86)

Sex

 Male, N (%)

26 (52)

33 (54.1)

36 (41.9)

 Female, N (%)

24 (48)

28 (45.9)

50 (58.1)

Age (years)

45.150 ± 1.400

46.220 ± 1.600

60.110 ± 2.100

miR-101-3p

1.000 ± 0.145

0.816 ± 0.068*

0.730 ± 0.064*#

PGI (μg/l)

75.460 ± 12.480

66.770 ± 9.240*

58.490 ± 11.950*#

PGII (μg/l)

11.000 ± 3.380

14.870 ± 9.090*

17.790 ± 16.010*#

PGI/II ratio

7.350 ± 1.970

5.440 ± 2.040*

4.220 ± 1.710*#

CEA (μg/l)

1.850 ± 0.730

2.310 ± 1.080

3.660 ± 1.380*#

  1. Notes: PG Pepsinogen, AG Atrophic gastritis, GC Gastric cancer, CEA Carcinoembryonic antigen; Quantitative data were expressed as mean ± standard deviation (SD), and the difference was analyzed by ANOVA, followed by Tukey’s multiple comparison test. Qualitative data were expressed as number (percentage), and the difference was determined by X2 test. *, P <  0.05 compared with normal control; #, P <  0.05 compared with AG