| Rs4977574 (A > G) | CHD (n = 598) | Control (n = 257) | OR(95% CI) | P value | AOR*(95% CI) | P* value |
|---|
| AA | 149 | 87 | 1.000 (reference) | 0.012 | 1.000 (reference) | 0.005 |
| AG | 297 | 122 | 1.849 (1.217–2.810) | 0.004 | 2.035 (1.323–3.132) | 0.001 |
| GG | 152 | 48 | 1.421 (1.014–1.993) | 0.042 | 1.452 (1.026–2.054) | 0.035 |
| Dominant model (AAvsAG+GG) | 149/449 | 87/170 | 1.542 (1.122–2.119) | 0.008 | 1.612(1.163–2.235) | 0.004 |
| Recessive model (GGvsAA+AG) | 152/446 | 48/209 | 0.674 (0.468–0.970) | 0.033 | 0.620 (0.427–0.902) | 0.012 |
| Allele A frequency | 595 (49.75%) | 296 (57.59%) | OR(95% CI) | P value | AOR*(95% CI) | P* value |
| Allele G frequency | 601 (50.25%) | 218 (42.41%) | | | | |
| HWE | 0.871 | 0.651 | | | | |
| RS1333045 (C > T) | CHD (n = 598) | Control (n = 257) | | | | |
| CC | 168 | 57 | 1.000 (reference) | 0.108 | 1.000 (reference) | 0.060 |
| TC | 292 | 127 | 0.641 (0.424–0.970) | 0.035 | 0.599 (0.392–0.915) | 0.018 |
| TT | 138 | 73 | 0.780 (0.541–1.124) | 0.183 | 0.759 (0.522–1.105) | 0.151 |
| Dominant model (CCvsTC+TT) | 168/430 | 57/200 | 0.729 (0.517–1.029) | 0.072 | 0.700 (0.492–0.997) | 0.048 |
| Recessive model (TTvsCC+TC) | 138/460 | 73/184 | 1.322 (0.950–1.842) | 0.098 | 1.392 (0.991–1.955) | 0.057 |
| Allele C frequency | 628 (52.51%) | 241 (46.89%) | | | | |
| Allele T frequency | 568 (47.49%) | 273 (53.11%) | | | | |
| HWE | 0.609 | 0.900 | | | | |
- In the SNP rs4977574, GG represents the homozygote of minor alleles, AG represents the heterozygote, and AA represents the homozygote of major alleles. In the SNP rs1333045, TT represents the homozygote of minor alleles, TC represents the heterozygote, and CC represents the homozygote of major alleles
- AOR Adjusted odds ratio
- *Adjusted for age and gender
