Table 6 Logistic analysis of the association between SNPs rs4977574 and rs1333045 and CHD risk

AA

149

87

1.000 (reference)

0.012

1.000 (reference)

0.005

AG

297

122

1.849 (1.217–2.810)

0.004

2.035 (1.323–3.132)

0.001

GG

152

48

1.421 (1.014–1.993)

0.042

1.452 (1.026–2.054)

0.035

Dominant model (AAvsAG+GG)

149/449

87/170

1.542 (1.122–2.119)

0.008

1.612(1.163–2.235)

0.004

Recessive model (GGvsAA+AG)

152/446

48/209

0.674 (0.468–0.970)

0.033

0.620 (0.427–0.902)

0.012

Allele A frequency

595 (49.75%)

296 (57.59%)

OR(95% CI)

P value

AOR*(95% CI)

P* value

Allele G frequency

601 (50.25%)

218 (42.41%)

HWE

0.871

0.651

RS1333045 (C > T)

CHD (n = 598)

Control (n = 257)

CC

168

57

1.000 (reference)

0.108

1.000 (reference)

0.060

TC

292

127

0.641 (0.424–0.970)

0.035

0.599 (0.392–0.915)

0.018

TT

138

73

0.780 (0.541–1.124)

0.183

0.759 (0.522–1.105)

0.151

Dominant model (CCvsTC+TT)

168/430

57/200

0.729 (0.517–1.029)

0.072

0.700 (0.492–0.997)

0.048

Recessive model (TTvsCC+TC)

138/460

73/184

1.322 (0.950–1.842)

0.098

1.392 (0.991–1.955)

0.057

Allele C frequency

628 (52.51%)

241 (46.89%)

Allele T frequency

568 (47.49%)

273 (53.11%)

HWE

0.609

0.900