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Table 6 The association between UCPs and sight threatening diabetic retinopathy in participants with and without controlled glucose

From: Analysis of association between common variants of uncoupling proteins genes and diabetic retinopathy in a Chinese population

rs ID

A1a

All sub-group participants (127 cases vs 1268 controls)

Well controlled glucose (23 cases vs 657 controls)

Uncontrolled glucose (104 cases vs 611 controls)

ORb [95% CIc]

P

OR [95% CI]

P

OR [95% CI]

P

rs6818140

G

2.773 [0.636–12.085]

0.174

11.773 [0.832–166.650]

0.068

1.610 [0.336–7.722]

0.552

rs7688743

A

0.241 [0.058–1.005]

0.051

0.049 [0.004–0.672]

0.024

0.425 [0.092–1.954]

0.272

rs10011540

G

2.612 [0.592–11.528]

0.205

18.758 [1.006–349.653]

0.050

1.448 [0.304–6.907]

0.642

rs3811787

T

0.490 [0.293–0.822]

0.007

0.505 [0.158–1.617]

0.250

0.467 [0.251–0.871]

0.017

rs3811790

A

1.111 [0.687–1.798]

0.667

1.919 [0.612–6.015]

0.264

1.125 [0.643–1.970]

0.679

rs3811791

C

0.689 [0.385–1.234]

0.211

0.704 [0.187–2.644]

0.603

0.608 [0.299–1.238]

0.170

rs1472268

A

0.906 [0.005–166.826]

0.970

0.001 [< 0.01- > 999]

0.982

> 999 [< 0.01- > 999]

0.959

rs1800592

T

1.282 [0.007–236.211]

0.926

> 999 [< 0.01- > 999]

0.981

< 0.01 [< 0.01- > 999]

0.959

rs659366

T

2.790 [0.533–14.599]

0.224

0.506 [0.066–3.899]

0.513

5.665 [0.812–39.498]

0.080

rs591758

C

0.222 [0.040–1.237]

0.086

1.244 [0.125–12.341]

0.852

0.103 [0.014–0.762]

0.026

rs1685356

T

1.004 [0.699–1.443]

0.981

0.592 [0.262–1.340]

0.209

1.203 [0.793–1.826]

0.384

rs3741135

A

1.565 [0.838–2.924]

0.160

1.182 [0.343–4.068]

0.791

1.770 [0.819–3.825]

0.146

rs2734827

A

0.881 [0.481–1.615]

0.683

0.381 [0.050–2.922]

0.354

1.217 [0.618–2.399]

0.570

  1. a A1 effect allele, b OR odds ratio, c CI confidence Interval