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Table 4 The association between environmental factors and diabetic retinopathy in participants with and without controlled glucose

From: Analysis of association between common variants of uncoupling proteins genes and diabetic retinopathy in a Chinese population

 

Diabetic retinopathy

Sight threatening diabetic retinopathy

Well controlled glucose

Uncontrolled glucose

Well controlled glucose

Uncontrolled glucose

Case

Control

p

Case

Control

p

Case

Control

p

Case

Control

p

n

172

684

 

356

660

 

23

657

 

104

611

 

age (year)

67.04 ± 9.89

67.32 ± 9.34

0.73

67.97 ± 10.18

68.62 ± 9.13

0.32

71.87 ± 6.58

67.11 ± 9.22

0.01

69.58 ± 10.10

68.29 ± 9.08

0.19

male

66 (38.37)

254 (37.13)

0.76

159 (44.66)

285 (43.18)

0.65

8 (34.78)

243 (36.99)

0.83

51 (49.04)

264 (43.21)

0.27

diabetes duration

5.88 ± 6.00

4.45 ± 4.88

0.01

11.61 ± 7.06

7.95 ± 6.07

< 0.01

7.11 ± 7.63

4.11 ± 4.64

0.13

13.25 ± 7.29

7.72 ± 6.10

< 0.01

BMIa

24.62 ± 2.86

24.46 ± 3.08

0.25

24.88 ± 3.45

25.08 ± 3.38

0.6

24.65 ± 3.05

24.81 ± 3.16

0.82

24.25 ± 3.56

25.15 ± 3.27

0.01

high blood pressure

125 (72.67)

472 (69.01)

0.4

286 (80.34)

515 (78.03)

0.42

17 (77.27)

448 (75.17)

0.82

93 (89.42)

519 (84.94)

0.23

hypercreatininemia

8 (4.65)

37 (5.41)

0.69

28 (7.87)

33 (5.00)

0.07

0 (0.00)

34 (5.18)

0.26

11 (10.58)

28 (4.59)

0.01

hypercholesterolemia

68 (39.53)

295 (43.13)

0.39

167 (46.91)

277 (42.03)

0.14

9 (39.13)

288 (43.84)

0.65

48 (46.15)

261 (42.03)

0.52

hyperlipidemia

40 (23.26)

198 (28.95)

0.14

134 (37.64)

245 (37.18)

0.88

2 (8.7)

191 (29.07)

0.03

34 (32.69)

232 (38.03)

0.3

HbA1cb (%)

5.93 ± 0.38

5.92 ± 0.38

0.89

8.27 ± 1.46

7.69 ± 1.08

< 0.01

6.06 ± 0.36

5.92 ± 0.37

0.08

8.44 ± 1.57

7.70 ± 1.09

< 0.01

  1. aBMI body mass index, bHbA1c hemoglobin A1c