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Table 1 The association between uncoupling proteins genes variants and diabetic retinopathy

From: Analysis of association between common variants of uncoupling proteins genes and diabetic retinopathy in a Chinese population

Chr.a

rs ID

Position (hg19)

A1b

Dataset 1 (528 cases vs 1344 controls)

Dataset 2 (134 cases vs 1101 controls)

Meta-analysis

ORc [95% CId]

P

OR [95% CI]

P

OR

P

Padje

Qf

4

rs6818140

141,487,955

G

1.028 [0.852–1.240]

0.772

1.190 [0.870–1.629]

0.277

1.068

0.421

1.000

0.4326

4

rs7688743

141,488,795

A

1.152 [0.982–1.351]

0.083

1.322 [0.999–1.750]

0.050

1.192

0.013

0.173

0.4028

4g

rs10011540

141,489,996

G

1.312 [1.031–1.670]

0.027

1.571 [1.012–2.438]

0.043

1.368

0.004

0.048

0.4814

4

rs3811787

141,490,419

T

0.861 [0.747–0.993]

0.039

0.870 [0.657–1.151]

0.328

0.863

0.023

0.293

0.9501

4

rs3811790

141,491,576

A

0.946 [0.816–1.098]

0.466

0.938 [0.718–1.225]

0.638

0.944

0.387

1.000

0.9549

4

rs3811791

141,491,773

C

0.973 [0.823–1.150]

0.745

0.874 [0.642–1.190]

0.391

0.949

0.488

1.000

0.5499

4

rs1472268

141,492,943

A

1.007 [0.873–1.161]

0.926

0.991 [0.769–1.277]

0.943

1.003

0.961

1.000

0.9130

4

rs1800592

141,493,961

T

0.996 [0.864–1.148]

0.959

1.015 [0.787–1.308]

0.910

1.001

0.993

1.000

0.9013

11

rs659366

73,694,754

T

0.998 [0.862–1.156]

0.983

1.249 [0.965–1.617]

0.091

1.055

0.414

1.000

0.1394

11

rs591758

73,698,060

C

0.989 [0.854–1.145]

0.882

1.206 [0.932–1.561]

0.154

1.038

0.567

1.000

0.1896

11

rs1685356

73,712,859

T

1.053 [0.913–1.215]

0.477

0.910 [0.699–1.185]

0.485

1.019

0.770

1.000

0.3415

11

rs3741135

73,713,960

A

1.022 [0.882–1.184]

0.772

1.305 [1.003–1.698]

0.047

1.083

0.223

1.000

0.1123

11

rs2734827

73,716,277

A

0.990 [0.743–1.320]

0.947

0.868 [0.605–1.247]

0.444

0.941

0.597

1.000

0.5774

  1. a Chr., chromosome; b A1, effect allele; c OR, odds ratio; d CI, confidence Interval; e Padj, Bonferroni correction based on the total number of markers tested (n = 13); f Cochran’s Q statistic; g The SNP with corrected P < 0.05 in the meta-analysis was marked in bold