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Table 6 Meta-analysis of TNF-α 1031 T/C polymorphisms and CAD susceptibility

From: Association of tumor necrosis factor-α gene polymorphisms and coronary artery disease susceptibility: a systematic review and meta-analysis

Genetic Model

N (case/control)

OR(95%CI)

P*

I2

P#

P value

Begg

Egger

CC vs TT + CT

3781/3845

1.020 (0.677,1.539)

0.013

58.6%

0.923

0.602

0.458

CC + CT vs TT

3781/3845

0.945 (0.860,1.039)

0.476

0.0%

0.243

0.466

0.786

CC vs TT

3781/3845

0.999 (0.666,1.498)

0.018

56.5%

0.997

0.602

0.465

CT vs TT

3781/3845

0.929 (0.842,1.025)

0.401

4.1%

0.141

0.175

0.951

C vs T

3781/3845

0.973 (0.898,1.054)

0.248

21.9%

0.505

1.000

0.624

  1. *P value of Heterogeneity chi-squared
  2. #P value of Pooled statistic