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Fig. 2 | BMC Medical Genetics

Fig. 2

From: Mice lacking global Stap1 expression do not manifest hypercholesterolemia

Fig. 2

Baseline metabolic parameters in chow-fed Stap1−/− and control mice. Panel a shows the starting body composition of mice at age 5–6 weeks on a chow diet (n = 6–7). Starting lean or fat masses between wildtype and knockout mice were comparable. Glucose tolerance (Panel b, n = 6), plasma cholesterol (Panel c, n = 6), triglycerides (Panel d, n = 6) were also comparable and showed no statistical differences. Panel e shows the FPLC cholesterol profiles in 10–11 weeks old male Stap1+/+ and Stap1−/− mice and was also indistinguishable. Note that the knockout mice do not show any differences in the VLDL (fractions 3–6), or LDL (fractions 20–28) ranges. Error bars denote ±1 SD

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