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Table 2 Distribution of genotype and allele among asthma patients and controls

From: Interleukin-4 gene polymorphism (C33T) and the risk of the asthma: a meta-analysis based on 24 publications

Study author Asthma cases Healthy control P-HWE MAF
  CC CT TT C T CC CT TT C T  
Suzuki et al. 11 56 53 78 162 10 59 51 79 161 0/21 0/67
Beghe et al. 140 41 6 321 53 132 48 2 312 52 0/29 0/142
Basehore et al. (i) 153 72 8 378 88 185 56 4 426 64 0/91 0/13
Basehore et al.(ii) 51 83 34 185 151 87 132 50 306 232 0/99 0/431
Basehore et al.(iii) 48 53 15 149 83 60 57 13 177 83 0/92 0/319
Park et al. 19 164 349 202 862 7 57 106 71 269 0/84 0/791
Donfack et al. (i) 83 37 6 203 49 150 50 5 350 60 0/73 0/146
Donfack et al.(ii) 68 107 30 243 167 70 86 27 226 140 0/94 0/382
Garcia et al. 93 39 1 225 41 64 15 0 143 15 0/35 0/094
Battle et al. 85 128 48 298 224 57 87 32 201 151 0/9 0/428
Amirzargar et al. 2 56 1 60 58 61 78 0 200 78 < 0.001 0/28
Jiang et al. 0 9 15 9 39 2 10 12 14 34 0/96 0/708
Daley et al. 481 150 12 1112 174 555 181 15 1291 211 0/95 0/14
Haller et al. 21 36 15 78 66 27 33 10 87 53 0/98 0/378
Wang et al. 22 147 277 191 701 16 186 308 218 802 0/05 0/786
Berce et al. 67 31 8 165 47 51 35 3 137 41 0/3 0/23
Undarmaa et al. (i) 27 142 155 196 452 37 144 155 218 454 0/68 0/675
Undarmaa et al.(ii) 28 154 185 210 524 64 286 326 414 938 0/91 0/693
Wu et al. 6 83 163 95 409 11 87 129 109 345 0/44 0/759
Michel et al. 458 210 35 1126 280 474 173 11 1121 195 0/28 0/148
Huang et al. 1 23 76 25 175 3 49 70 55 189 0/09 0/774
Yang et al. 14 56 132 84 320 7 67 131 81 329 0/65 0/802
Chen et al. 6 72 124 84 320 6 62 123 74 308 0/58 0/806
Micheal et al. 77 31 0 185 31 93 27 0 213 27 0/16 0/112
Miyake et al. 12 33 44 57 121 160 604 517 924 1638 0/42 0/639
Davoodi et al. 65 31 4 161 39 36 14 0 86 14 0/24 0/14
Wang et al. 49 176 167 274 510 102 410 337 614 1084 0/18 0/638
Li et al. 147 170 0 464 170 170 181 0 521 181 < 0.001 0/257
  1. P-HWE, p-value for Hardy–Weinberg equilibrium; MAF, minor allele frequency of control group