|
SNP
|
Chr
|
Base Position
|
Near gene
|
Reference allele
|
MAF
|
OR
|
95% CI
|
P-value
|
|---|
|
–
|
5
|
10,847,898
|
DAPa
|
C
|
–
|
6.87
|
3.41–13.84
|
7.15 × 10−8
|
|
rs143668247
|
1
|
199,701,882
|
NR5A2
|
C
|
0.35
|
3.66
|
2.24–5.97
|
2.03 × 10−7
|
|
rs200516199
|
17
|
29,917,727
|
MIR365–2
|
TTTGA
|
0.04
|
7.71
|
3.54–16.78
|
2.63 × 10− 7
|
|
rs116834259
|
20
|
42,742,258
|
JPH2
|
T
|
0.11
|
4.42
|
2.50–7.81
|
3.15 × 10− 7
|
|
rs11452236
|
20
|
42,751,590
|
JPH2
|
C
|
0.13
|
4.03
|
2.34–6.92
|
4.78 × 10− 7
|
|
rs74358070
|
20
|
42,727,587
|
JPH2
|
T
|
0.11
|
4.24
|
2.41–7.47
|
5.52 × 10−7
|
|
rs16832308
|
2
|
133,253,243
|
GPR390
|
A
|
0.04
|
6.30
|
3.05–13.01
|
6.49 × 10−7
|
|
rs62167448
|
2
|
133,254,091
|
GPR39
|
C
|
0.04
|
6.30
|
3.05–13.01
|
6.49 × 10−7
|
|
rs150410476
|
11
|
37,223,676
|
C11orf74
|
A
|
0.03
|
8.31
|
3.60–19.16
|
6.80 × 10−7
|
|
rs12740341
|
1
|
199,699,781
|
NR5A2
|
C
|
0.26
|
3.18
|
2.01–5.03
|
7.94 × 10−7
|
|
rs79032354
|
20
|
42,732,460
|
JPH2
|
C
|
0.13
|
3.91
|
2.27–6.71
|
7.96 × 10−7
|
|
rs6130527
|
20
|
42,733,946
|
JPH2
|
G
|
0.13
|
3.91
|
2.27–6.71
|
7.96 × 10−7
|
|
rs4810411
|
20
|
42,751,472
|
JPH2
|
C
|
0.13
|
3.81
|
2.24–6.50
|
7.99 × 10−7
|
|
rs2502139
|
1
|
199,695,633
|
NR5A2
|
A
|
0.27
|
3.17
|
2.00–5.02
|
8.94 × 10−7
|
|
rs34026413
|
1
|
199,695,074
|
NR5A2
|
A
|
0.27
|
3.10
|
1.97–4.88
|
7.94 × 10−6
|
|
–
|
1
|
26,304,144
|
PAFAH2a
|
C
|
–
|
10.19
|
4.01–25.92
|
7.94 × 10− 6
|
|
rs543084794
|
2
|
133,250,145
|
GPR39a
|
C
|
0.04
|
6.44
|
3.04–13.65
|
7.94 × 10− 6
|
|
rs79014529
|
20
|
42,717,781
|
TOX2
|
C
|
0.13
|
3.81
|
2.22–6.53
|
7.94 × 10− 6
|
|
rs1429702
|
1
|
199,694,059
|
NR5A2
|
T
|
0.27
|
3.10
|
1.96–4.87
|
7.94 × 10−6
|
|
rs6130520
|
20
|
42,716,399
|
TOX2
|
G
|
0.13
|
3.77
|
2.20–6.47
|
7.94 × 10−6
|
- For this analysis, 51 women with hrHPV infection at both the baseline and follow-up visits were compared to 355 women without hrHPV infections at either the baseline or follow-up visits. Base positions were based on hg19; aThe variant is not in 1000 genomes v1, the nearest gene was obtained from variants surrounding the base location on the specific chromosome; Odds Ratio (OR) and 95% Confidence Intervals (CI) were estimated using an additive genetic model; Models were adjusted for age, HIV status and the first principal components of the genotypes
