Fig. 3

Homology models of the wild-type PIK3R1 and p.Gln654* mutant PIK3R1. The inter src-homology 2(iSH2) domain and C-terminal src-homology (cSH2) domain are shown in yellow and green respectively, with the PIK3R1 G654 shown in red

Homology models of the wild-type PIK3R1 and p.Gln654* mutant PIK3R1. The inter src-homology 2(iSH2) domain and C-terminal src-homology (cSH2) domain are shown in yellow and green respectively, with the PIK3R1 G654 shown in red