Fig. 3From: A novel PIK3R1 mutation of SHORT syndrome in a Chinese female with diffuse thyroid disease: a case report and review of literatureHomology models of the wild-type PIK3R1 and p.Gln654* mutant PIK3R1. The inter src-homology 2(iSH2) domain and C-terminal src-homology (cSH2) domain are shown in yellow and green respectively, with the PIK3R1 G654 shown in redBack to article page