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Table 3 Relationships between the candidate SNPs and cervical cancer risk according to the stratification by age

From: Genetic polymorphisms of PGF and TNFAIP2 genes related to cervical cancer risk among Uygur females from China

SNP ID Model Genotype >  43 years ≤ 43 years
Case Control OR (95%CI) p Case Control OR (95%CI) p
PGF
rs2268615
Allele C 253 393 1.00 0.303 223 344 1.00 0.041
A 99 131 1.17 (0.87–1.59) 109 122 1.38 (1.01–1.88)
Genotype CC 89 147 1.00   71 126 1.00  
CA 75 99 1.25 (0.84–1.86) 0.282 81 92 1.55 (1.02–2.36) 0.039
AA 12 16 1.22 (0.55–2.70) 0.626 14 15 1.62 (0.74–3.56) 0.228
Dominant CC 89 147 1.00 0.269 71 126 1.00 0.030
CA-AA 87 115 1.24 (0.85–1.82) 95 107 1.56 (1.05–2.33)
Recessive CC-CA 164 246 1.00 0.795 152 218 1.00 0.481
AA 12 16 1.11 (0.51–2.41) 14 15 1.31 (0.61–2.81)
Log-additive 1.17 (0.86–1.60) 0.317 1.40 (1.01–1.92) 0.042
TNFAIP2
rs710100
Allele G 217 331 1.00 0.597 190 300 1.00 0.018
A 135 191 1.08 (0.82–1.43) 142 158 1.42 (1.06–1.90)
Genotype GG 64 111 1.00   54 99 1.00  
GA 89 109 1.41 (0.93–2.14) 0.105 82 102 1.46 (0.94–2.27) 0.092
AA 23 41 0.96 (0.53–1.74) 0.890 30 28 1.97 (1.07–3.63) 0.031
Dominant GG 64 111 1.00 0.208 54 99 1.00 0.034
GA-AA 112 150 1.29 (0.87–1.91) 112 130 1.57 (1.03–2.38)
Recessive GG-GA 153 220 1.00 0.418 136 201 1.00 0.103
AA 23 41 0.80 (0.46–1.38) 30 28 1.59 (0.91–2.79)
Log-additive 1.07 (0.81–1.41) 0.635 1.42 (1.06–1.90) 0.020
  1. SNP single nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
  2. p values were calculated by logistic regression analysis with adjustments for age
  3. p < 0.05 indicates statistical significance