Table 3 Association between DNMT3A rs6733868 and CpG methylation of each genes
From: Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa
genotype | p14ARF-UM (343) | p14ARF-M (167) | adjusted OR* (95%CI); p value | |
CC | 131 | 81 | reference | reference |
CG | 163 | 61 | 0.67 (0.46–0.98); 0.038 | |
GG | 49 | 25 | 1.07 (0.629–1.82); 0.80 | |
genotype | p16INK4a-UM (376) | p16INK4a-M (134) | adjusted OR* (95%CI); p value | |
CC | 143 | 69 | reference | reference |
CG | 175 | 49 | 0.60 (0.40–0.91); 0.015 | |
GG | 58 | 16 | 0.78 (0.42–1.44); 0.42 | |
genotype | DAPK-UM (258) | DAPK-M (252) | adjusted OR* (95%CI); p value | |
CC | 90 | 122 | reference | reference |
CG | 112 | 112 | 0.59 (0.41–0.85); 0.0050 | |
GG | 56 | 18 | 0.28 (0.15–0.49); < 0.0001 | |
genotype | CDH1-UM (318) | CDH1-M (192) | adjusted OR* (95%CI); p value | |
CC | 112 | 100 | refernce | reference |
CG | 154 | 70 | 0.52 (0.36–0.75); 0.0005 | |
GG | 52 | 22 | 0.70 (0.40–1.20); 0.19 | |