Table 4 Clinical and haematological parameters in the deletion and non-deletion types HbH Disease
From: Genotype-phenotype correlation of HbH disease in northern Iraq
Parameters | Deletion (31 cases) | Non-Deletion (13 cases) | p-value |
|---|---|---|---|
RBC count, (median, range) | 5.05 (3.5–6.61) | 4.51 (2.96–6.74) | 0.069 |
Hb, g/dL (median, range) | 9.2 (8.0–11.5) | 8.3 (6.4–12.7) | 0.086 |
MCV, fl (median, range) | 61.3 (52.2–68.7) | 62.6 (52.5–81.9) | 0.309 |
MCH, pg (median, range) | 18.0 (16.1–21.9) | 18.9 (16.1–28) | 0.241 |
RDW, % (median, range) | 25.6 (16.9–30.7) | 25.0 (18.7–36.3) | 0.816 |
HbH, % (median, range) | 7.5 (1–15) | 7.2 (5.7–25.7) | 0.125 |
Ferritin, ng/mL (median, range) | 467 (11–2950) | 389 (29–1726) | 0.403 |
Splenectomized | 4 (12.9%) | 1 (7.7) | 0.20 |
Transfusion | |||
Never transfused | 16 (51.6%) | 7 (53.8%) | 0.57 |
Occasional (≤1 unit per year) | 13 (41.9%) | 4 (30.8%) | |
Irregular (2 to 4 units per year) | 2 (6.5%) | 2 (15.4%) | |