Skip to main content

Table 6 Association between MIF polymorphisms and CDKN2A methylation

From: Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitis

rs755622

GG vs. GC + CC

GG + GC vs. CC

adjusted OR* (95% CI); p value

adjusted OR* (95% CI); p value

Neither methylated (77)

reference

reference

Both methylated (42)

2.70 (1.22–6.01); p = 0.015

3.92 (0.76–20.3); p = 0.10

rs5844572

X/X vs. X/7 + 7/7

X/X + X/7 vs. 7/7

adjusted OR* (95% C.I.); p value

adjusted OR* (95% C.I.); p value

Neither methylated (77)

reference

reference

Both methylated (42)

2.87 (1.25–6.62); p = 0.013

12.0 (1.55–92.2); p = 0.017

  1. *by logistic regression analysis after adjustment for age, gender, clinical type and disease extension
  2. X: 5 or 6 repeat allele; 7: 7 repeat allele
Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us