Table 5 Demographic characteristics and allele frequencies of subjects demonstrating no methylation or methylation of both p14^ARF and p16^INK4a

Number of sample

77

42

Mean age ± SD

41.6 ± 14.9

42.5 ± 12.9

NS

Male: female

46: 31

21: 21

NS

Clinical type

NS

 Chronic continuous

25

12

 Relapse/remitting

52

30

Extension

NS

 Total colitis

31

21

Distal or left side colitis (rs755622 G > C)

46

21

 GG

49

17

0.020

 GC

24

21

 CC

4

4

NS

 C allele freqency (rs5844572 CATT repeat)

20.8%

34.5%

0.029

 5/5

7

1

 5/6

27

13

 5/7

12

12

 6/6

19

5

 6/7

10

7

 7/7

2

4

 5 repeat freqency

34.4%

32.1%

 6 repeat freqency

48.7%

35.7%

 7 repeat freqency

16.9%

32.1%

0.0090