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Table 4 Association between MIF rs5844572 and CDKN2A methylation

From: Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitis

 

Genotype (repeat number)

X/X vs. X/7 + 7/7

X/X + X/7 vs. 7/7

5/5

5/6

5/7

6/6

6/7

7/7

adjusted OR* (95% CI); p value

adjusted OR* (95% CI); p value

p14-UM (105)

13

40

16

19

14

3

reference

reference

p14-M (54)

3

17

12

9

9

4

1.77 (0.864–3.63); p = 0.12

4.51 (0.79–25.7); p = 0.090

p16-UM (89)

9

31

12

23

12

2

reference

reference

p16-M (70)

7

26

16

5

11

5

2.57 (1.26–5.24); p = 0.0094

5.51 (0.90–33.9); p = 0.066

  1. *by logistic regression analysis after adjustment for age, gender, clinical type and disease extension
  2. UM Unmethylated, M Methylated, X: 5 or 6 repeat allele; 7: 7 repeat allele
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BMC Medical Genetics

ISSN: 1471-2350

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