Table 2 Demographic characteristics, allelic frequencies, and CDKN2A methylation status

Number of sample

159

105

54

89

70

Mean age ± SD

41.3 ± 13.6

40.4 ± 13.4

43.0 ± 14.0

NS

42.1 ± 15.2

40.2 ± 11.3

NS

Male: female

91: 68

66: 39

25: 29

NS

50: 39

41: 29

NS

Clinical type

NS

NS

 Chronic continuous

56

38

18

31

25

 Relapse/remitting

103

67

36

58

45

Disease extension

NS

NS

 Total colitis

74

49

25

35

39

 Distal or left side colitis (rs755622 G > C)

85

56

29

54

31

 GG

93

68

25

0.010

57

36

NS

 GC

57

32

25

28

29

 CC

9

5

4

NS

4

5

NS

 C allele freqency (rs5844572 CATT repeat)

23.6%

20.0%

30.6%

0.050

20.2%

27.9%

NS

 5/5

16

13

3

9

7

 5/6

57

40

17

31

26

 5/7

28

16

12

12

16

 6/6

28

19

9

23

5

 6/7

23

14

9

12

11

 7/7

7

3

4

2

5

 5 repeat freqency

36.8%

39.0%

32.4%

34.3%

40.0%

 6 repeat freqency

42.8%

43.8%

40.7%

50.0%

42.1%

 7 repeat freqency

20.4%

17.1%

26.9%

NS

15.7%

26.4%

0.036