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Table 3 Genotypic distribution of the investigated variants for patients with GC in comparison to control group. P-value, OR and 95%CI were obtained with logistic regression adjusted for age, which was done for the genotype as reference in each line (DEL/DEL vs. the other genotypes of that marker, and the same for INS/DEL and INS/INS)

From: Investigation of INDEL variants in apoptosis: the relevance to gastric cancer

Gene Genotype Case (%)* Control (%)* P-value OR (95%CI)
BCL2 rs11269260 93 98   
DEL/DEL 13 (14) 19 (19.4) 0.844 1.090 (0.463–2.567)
INS/DEL 51 (54.8) 42 (42.9) 0.149 1.589 (0.848–2.977)
INS/INS 29 (31.2) 37 (37.8) 0.092 0.556 (0.281–1.101)
CASP3 rs4647655 93 96   
DEL/DEL 47 (50.5) 48 (50.0) 0.898 0.959 (0.511–1.802)
INS/DEL 39 (41.9) 39 (40.6) 0.995 1.002 (0.528–1.904)
INS/INS 7 (7.5) 9 (9.4) 0.825 1.136 (0.365–3.537)
CASP8 rs3834129 93 98   
DEL/DEL 27 (29.0) 19 (19.4) 0.098 1.851 (0.893–3.835)
INS/DEL 38 (40.9) 42 (42.9) 0.987 0.995 (0.526–1.880)
INS/INS 28 (30.1) 37 (37.7) 0.132 0.596 (0.303–1.169)
rs59308963 89 93   
DEL/DEL 30 (33.7) 29 (31.2) 0.749 1.116 (0.568–2.195)
INS/DEL 41 (46.1) 44 (47.3) 0.727 0.893 (0.471–1.690)
INS/INS 18 (20.2) 20 (21.5) 0.953 1.024 (0.467–2.244)
CASP9 rs4645982 81 58   
DEL/DEL 16 (19.8) 13 (22.4) 0.897 0.943 (0.392–2.272)
INS/DEL 24 (29.6) 20 (34.5) 0.583 0.808 (0.377–1.732)
INS/INS 41 (50.6) 25 (43.1) 0.535 1.254 (0.613–2.567)
rs61079693 89 94   
DEL/DEL 22 (24.7) 26 (27.7) 0.418 0.742 (0.360–1.529)
INS/DEL 46 (51.7) 44 (46.8) 0.765 1.102 (0.585–2.076)
INS/INS 21 (23.6) 24 (25.5) 0.621 1.209 (0.570–2.563)
FADD rs4197 93 97   
DEL/DEL 31 (33.3) 41 (42.3) 0.099 0.573 (0.295–1.111)
INS/DEL 57 (61.3) 48 (49.5) 0.046 1.940 (1.011–3.725)
INS/INS 5 (5.4) 8 (8.2) 0.441 0.600 (0.163–2.202)
FAS rs10562972 89 93   
DEL/DEL 1 (1.1) 0 (0.0) 0.988 991,452.554 (0.000–∞)
INS/DEL 10 (11.2) 21 (22.6) 0.260 0.603 (0.250–1.454)
INS/INS 78 (87.6) 72 (77.4) 0.329 1.535 (0.650–1.125)
TP53 rs17880560 87 93   
DEL/DEL 57 (65.5) 58 (62.4) 0.738 1.119 (0.579–2.166)
INS/DEL 26 (29.9) 31 (33.3) 0.714 0.880 (0.445–1.741)
INS/INS 4 (4.6) 4 (4.3) 0.964 1.035 (0.232–4.623)
  1. *Sample number; P-value: P-value adjusted for age, OR Odds Ratio, CI Confidence Interval