Genetic risk-factors for anxiety in healthy individuals: polymorphisms in genes important for the HPA axis

BMC Medical Genetics

Table 2 Allele and genotype frequencies of the five polymorphisms studied

Polymorphism	Allele	Allelle frequency	Genotype	Genotype frequency	Hardy-Weinberg Equilibrium
5-HTTLPR N = 72	s	0.451	s/s	0.264	χ2 = 4.26 p = 0.04
	l	0.549	s/l	0.375
			l/l	0.361
rs6295 N = 72	C	0.507	CC	0.261	χ2 = 0.01 p = 0.91
	G	0.493	CG	0.493
			GG	0.246
rs41423247 N = 72	C	0.364	CC	0.086	χ2 = 2.60, p = 0.11
	G	0.636	CG	0.557
			GG	0.357
rs1360780 N = 72	C	0.696	CC	0.507	χ2 = 0.83, p = 0.36
	T	0.304	CT	0.377
			TT	0.116
rs53576 N = 72	A	0.357	AA	0.072	χ2 = 2.32, p = 0.13
	G	0.643	AG	0.551
			GG	0.373

ISSN: 1471-2350