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Table 8 Distribution of different well-known risk factors for cardiovascular mortality between the genotypes A/A and A/G or G/A amalgamated, of rs2228262 in the study population

From: Increased cardiovascular mortality in females with the a/a genotype of the SNPs rs1478604 and rs2228262 of thrombospondin-1

Variable   Total pop    Females    Males  
A/A A/G-G/G p-value A/A A/G-G/G p-value A/A A/G-G/G p-value
n 259 211   124 107   135 104  
IHD,n (%) 65 (25.1) 45 (21.3) 0.34 23 (18.5) 21 (19.6) 0.84 42 (31.1) 24 (23.1) 0.17
DM, n (%) 90 (34.7) 63 (29.9) 0.26 41 (33.1) 27 (25.2) 0.19 49 (36.3) 36 (34.6) 0.79
NYHA III, n (%) 57 (22.0) 37 (17.5) 0.23 27 (21.8) 19 (17.8) 0.45 30 (22.2) 18 (17.3) 0.35
AF, n (%) 31 (12.0) 15 (7.1) 0.08 12 (9.7) 6 (5.6) 0.25 19 (14.1) 9 (8.7) 0.20
EF < 40%, n (%) 19 (7.3) 17 (8.1) 0.77 6 (4.8) 3 (2.8) 0.43 13 (9.6) 14 (13.5) 0.35
Hb < 120 g/L, n (%) 25 (9.7) 26 (12.3) 0.35 17 (13.7) 16 (15.0) 0.79 8 (2.2) 10 (9.6) 0.28
  1. AF atrial fibrillation, DM diabetes mellitus, EF ejection fraction, IHD ischemic heart disease, NYHA New York Heart Association functional class