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Table 8 Distribution of different well-known risk factors for cardiovascular mortality between the genotypes A/A and A/G or G/A amalgamated, of rs2228262 in the study population

From: Increased cardiovascular mortality in females with the a/a genotype of the SNPs rs1478604 and rs2228262 of thrombospondin-1

Variable

 

Total pop

  

Females

  

Males

 

A/A

A/G-G/G

p-value

A/A

A/G-G/G

p-value

A/A

A/G-G/G

p-value

n

259

211

 

124

107

 

135

104

 

IHD,n (%)

65 (25.1)

45 (21.3)

0.34

23 (18.5)

21 (19.6)

0.84

42 (31.1)

24 (23.1)

0.17

DM, n (%)

90 (34.7)

63 (29.9)

0.26

41 (33.1)

27 (25.2)

0.19

49 (36.3)

36 (34.6)

0.79

NYHA III, n (%)

57 (22.0)

37 (17.5)

0.23

27 (21.8)

19 (17.8)

0.45

30 (22.2)

18 (17.3)

0.35

AF, n (%)

31 (12.0)

15 (7.1)

0.08

12 (9.7)

6 (5.6)

0.25

19 (14.1)

9 (8.7)

0.20

EF < 40%, n (%)

19 (7.3)

17 (8.1)

0.77

6 (4.8)

3 (2.8)

0.43

13 (9.6)

14 (13.5)

0.35

Hb < 120 g/L, n (%)

25 (9.7)

26 (12.3)

0.35

17 (13.7)

16 (15.0)

0.79

8 (2.2)

10 (9.6)

0.28

  1. AF atrial fibrillation, DM diabetes mellitus, EF ejection fraction, IHD ischemic heart disease, NYHA New York Heart Association functional class