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Table 2 The association of genetic variants in CR1 gene with Aβ deposition on AV-45 PET among all people

From: Impacts of CR1 genetic variants on cerebrospinal fluid and neuroimaging biomarkers in alzheimer’s disease

SNPs Gene regions Position (Chromosome) Major allele Minor allele Regions β P value
rs10494884 intron variant 1:207674531 G A temporal 0.03364 0.03392
frontal 0.03543 0.03845
SUVR 0.02647 0.04447
rs11118322 intron variant 1:207674706 T C temporal 0.03342 0.03448
frontal 0.03477 0.04155
rs1323721 intron variant 1:207649895 A G temporal 0.03245 0.04141
frontal 0.03381 0.04894
rs17259045 missense 1:207609362 A G frontal −0.0773 0.007581
temporal −0.06968 0.009251
SUVR −0.05298 0.01725
cingulate −0.07068 0.02512
parietal −0.06473 0.03033
rs41308433 intron variant 1:207699490 A C temporal −0.0427 0.04292
  1. CR1 complement component (3b/4b) receptor 1 gene, SNPs single nucleotide polymorphisms, amyloid protein, SUVR standardized uptake values ratios