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Table 1 Characteristics of the Heinz Nixdorf Recall study population

From: Risk prediction for coronary heart disease by a genetic risk score - results from the Heinz Nixdorf Recall study

  All Events/N
343/4041
Events N (%)
343 (8.5)
No Events N (%)
3693 (91.5)
pc
Age (years) a 58.9 ± 7.6 63.5 ± 7.8 58.9 ± 7.6 < 0.0001
Men 1919 (47.5) 219 (63.9) 1700 (46.0) < 0.0001
BMI (kg/m2) 27.7 ± 4.6 28.7 ± 4.2 27.72 ± 4.6 < 0.0001
Smoker 2291 (56.7) 211 (61.5) 2080 (56.3) 0.06
Diabetes 490 (12.1) 78 (22.7) 412 (11.1) < 0.0001
Systolic blood pressure (mmHg) 131.8 ± 20.2 142.5 ± 23.6 131.8 ± 20.2 < 0.0001
Diastolic blood pressure (mmHg) 81.3 ± 10.7 83.8 ± 12.3 81.3 ± 10.7 0.0004
Use of antihypertensive medication 1263 (31.3) 163 (47.5) 1100 (29.8) < 0.0001
log(CAC + 1) b 2.3 (0; 4.5) 4.8 (2.7; 6.1) 2.3 (0; 4.5) < 0.0001
CAC > 0 2734 (67.7) 298 (86.9) 2436 (65.9) < 0.0001
Use of lipid lowering medication 360 (9.5) 39 (12.2) 321 (9.3) 0.11
LDL-cholesterol (mg/dL) 146.8 ± 36.3 147.9 ± 34.7 146.8 ± 36.3 0.40
HDL-cholesterol (mg/dL) 59.4 ± 17.1 55.2 ± 16.8 59.4 ± 17.1 < 0.0001
Triglycerides (mg/dL) b 123.0 (89.0; 177.0) 141.0 (101.0; 203.0) 121.0 (88.0; 175.0) < 0.0001
Total cholesterol a 231.4 ± 38.7 232.2 ± 39.5 231.3 ± 38.6 0.73
Coronary artery disease GRS a 0.03 ± 0.003 0.04 ± 0.003 0.03 ± 0.003 0.006
  1. LDL low density lipoprotein, HDL high density lipoprotein, CAC coronary artery calcification, GRS genetic risk score. Data are given as number (percentage) unless otherwise indicated
  2. a Data are given as mean ± SD. b Data are given as median (Q1; Q3)
  3. cp are for differences between CHD stratified groups using χ2 or Fisher exact test, t test or Mann-Whitney U test