From: Genetic polymorphisms of PIP5K2A and course of schizophrenia
SNP | Genotype Allele | Frequency | Chi-square | p-value | OR | Cl 95% | |
---|---|---|---|---|---|---|---|
Group of patients with a continuous course of schizophrenia (n = 269) | Group of patients with an episodic course of schizophrenia (n = 115) | ||||||
rs10828317 | CC | 0.187 | 0.175 | 0.072 | 0.965 | 1.08 | 0.61–1.91 |
CT | 0.403 | 0.412 | 0.96 | 0.62–1.50 | |||
TT | 0.410 | 0.412 | 0.99 | 0.64–1.55 | |||
C | 0.388 | 0.382 | 0.030 | 0.870 | 1.03 | 0.75–1.41 | |
T | 0.612 | 0.618 | 0.97 | 0.71–1.34 | |||
rs8341 | CC | 0.387 | 0.426 | 6.559 | 0.038 | 0.85 | 0.54–1.32 |
CT | 0.502 | 0.383 | 1.63 | 1.04–2.54 | |||
TT | 0.112 | 0.191 | 0.53 | 0.29–0.97 | |||
C | 0.638 | 0.617 | 0.280 | 0.600 | 1.09 | 0.79–1.50 | |
T | 0.362 | 0.383 | 0.92 | 0.67–1.26 | |||
rs746203 | CC | 0.133 | 0.195 | 4.756 | 0.093 | 0.63 | 0.35–1.14 |
CT | 0.494 | 0.381 | 1.59 | 1.01–2.50 | |||
TT | 0.373 | 0.425 | 0.80 | 0.51–1.26 | |||
C | 0.380 | 0.385 | 0.010 | 0.900 | 0.98 | 0.71–1.35 | |
T | 0.620 | 0.615 | 1.02 | 0.74–1.41 | |||
rs10430590 | AA | 0.467 | 0.437 | 1.754 | 0.416 | 0.76 | 0.46–1.25 |
AT | 0.434 | 0.402 | 1.14 | 0.68–1.89 | |||
TT | 0.099 | 0.061 | 1.70 | 0.62–4.60 | |||
A | 0.684 | 0.738 | 1.690 | 0.190 | 0.77 | 0.52–1.14 | |
T | 0.316 | 0.262 | 1.30 | 0.87–1.94 | |||
rs946961 | CC | 0.108 | 0.023 | 5.976 | 0.049 | 5.17 | 1.20–22.21 |
CG | 0.478 | 0.529 | 0.82 | 0.50–1.33 | |||
GG | 0.414 | 0.448 | 0.87 | 0.53–1.42 | |||
C | 0.347 | 0.287 | 2.100 | 0.150 | 1.32 | 0.91–1.92 | |
G | 0.653 | 0.713 | 0.76 | 0.52–1.10 | |||
rs1132816 | AA | 0.621 | 0.685 | 1.959 | 0.376 | 0.75 | 0.45–1.26 |
AG | 0.294 | 0.270 | 1.13 | 0.66–1.94 | |||
GG | 0.085 | 0.045 | 1.97 | 0.66–5.89 | |||
A | 0.768 | 0.820 | 2.080 | 0.150 | 0.73 | 0.47–1.12 | |
G | 0.232 | 0.180 | 1.38 | 0.89–2.13 | |||
rs1417374 | AA | 0.129 | 0.151 | 3.735 | 0.154 | 0.83 | 0.41–1.67 |
AG | 0.469 | 0.349 | 1.65 | 0.99–2.75 | |||
GG | 0.402 | 0.500 | 0.67 | 0.41–1.10 | |||
A | 0.363 | 0.326 | 0.780 | 0.380 | 1.18 | 0.82–1.71 | |
G | 0.637 | 0.674 | 0.85 | 0.59–1.22 | |||
rs943190 | CC | 0.131 | 0.209 | 5.326 | 0.070 | 0.57 | 0.30–1.08 |
CT | 0.502 | 0.372 | 1.70 | 1.03–2.81 | |||
TT | 0.367 | 0.419 | 0.80 | 0.49–1.32 | |||
C | 0.382 | 0.395 | 0.090 | 0.760 | 0.95 | 0.66–1.35 | |
T | 0.618 | 0.605 | 1.06 | 0.74–1.51 | |||
rs943194 | GG | 0.118 | 0.123 | 0.506 | 0.776 | 0.95 | 0.44–2.06 |
GT | 0.489 | 0.444 | 1.20 | 0.72–1.99 | |||
TT | 0.392 | 0.432 | 0.85 | 0.51–1.42 | |||
G | 0.363 | 0.346 | 0.160 | 0.690 | 1.08 | 0.74–1.57 | |
T | 0.637 | 0.654 | 0.93 | 0.64–1.35 | |||
rs1171506 | AA | 0.097 | 0.037 | 2.938 | 0.230 | 2.80 | 0.82–9.55 |
AG | 0.413 | 0.432 | 0.92 | 0.56–1.54 | |||
GG | 0.490 | 0.531 | 0.85 | 0.51–1.40 | |||
A | 0.304 | 0.253 | 1.510 | 0.220 | 1.29 | 0.86–1.93 | |
G | 0.696 | 0.747 | 0.78 | 0.52–1.16 | |||
rs11013052 | AA | 0.083 | 0.048 | 1.762 | 0.414 | 1.82 | 0.61–5.46 |
AC | 0.365 | 0.333 | 1.15 | 0.68–1.94 | |||
CC | 0.552 | 0.619 | 0.76 | 0.46–1.25 | |||
A | 0.266 | 0.214 | 1.770 | 0.180 | 1.33 | 0.87–2.02 | |
C | 0.734 | 0.786 | 0.75 | 0.50–1.14 |