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Table 5 Odds ratios (OR) of polymorphic rs17782313 MC4R genotypes for cardiovascular disease in Korean men (n = 2896)

From: Association of MC4R (rs17782313) with diabetes and cardiovascular disease in Korean men and women

  

Normal

Cardiovascular Disease

Subjects

Genotype

N (%)

N (%)

ORa (95% CIb)

P-value

BMI < 24.75

TT

516 (61.4)

325 (53.4)

1.00 (reference)

 

TC/ CC

325 (38.6)

284 (46.6)

1.40 (1.12–1.74)*

0.0028

BMI > =24.75

TT

438 (57.5)

385 (56.3)

1.00 (reference)

 

TC/ CC

324 (42.5)

299 (43.7)

1.05 (0.85–1.30)

0.6461

  1. * significant of p < 0.05
  2. P for the interaction between obesity (BMI > = 24.75) and MC4R (rs17782313) =0.0753
  3. a Adjusted for age and BMI b CI, confidence interval