Table 4 Odds ratios (OR) of the polymorphic rs17782313 MC4R genotypes for cardiovascular disease in the population (n = 4259)
From: Association of MC4R (rs17782313) with diabetes and cardiovascular disease in Korean men and women
Subjects | Normal | Cardiovascular Disease | |||||
|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | ||||||
Genotype | N (%) | N (%) | OR (95% CIa) | P-value | OR (95% CI) | P-value | |
All | TT | 1439 (58.1) | 989 (55.5) | 1.00 (reference) | 1.00 (reference) | ||
TC /CC | 1038 (41.9) | 793 (44.5) | 1.13 (1.00–1.28) | 0.0599 | 1.11 (0.98–1.26) | 0.1174 | |
Men | TT | 954 (59.5) | 710 (54.9) | 1.00 (reference) | 1.00 (reference) | ||
TC/ CC | 649 (40.5) | 583 (45.1) | 1.22 (1.05–1.42)* | 0.0096 | 1.21 (1.04–1.41)* | 0.0144 | |
Women | TT | 485 (55.5) | 279 (57.1) | 1.00 (reference) | 1.00 (reference) | ||
TC/ CC | 389 (44.5) | 210 (42.9) | 0.94 (0.75–1.19) | 0.5990 | 0.89 (0.71–1.13) | 0.3474 | |