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Fig. 4 | BMC Medical Genetics

Fig. 4

From: Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain

Fig. 4

ESTIMATE immune scores by mutation frequency quartiles, E/Q/Z mutation groups, and MSI in colorectal [38], endometrial (UCEC) and stomach (STAD) cancers. a ESTIMATE immune scores in cancers within high, intermediate and low overall mutation quartiles. b Immune scores of samples with E/Q, E/Z and E/Q/Z mutations compared to the low mutation quartile from panel A. c Immune scores in groups of cancers separated by MSI status. d Immune scores in MSI and MSS E/Q/Z cases compared to all other MSI cases. For each panel the number of cases within each group is included in parentheses on the x-axis

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BMC Medical Genetics

ISSN: 1471-2350

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