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Table 4 Subgroup analysis of the association between rs1006737 and the risk of schizophrenia

From: The genome-wide supported CACNA1C gene polymorphisms and the risk of schizophrenia: an updated meta-analysis

Ancestor

Summary of pooled ORs

Heterogeneity test

OR

95% CI

P-value

I2(%)

Ph

Asian

Allele contrast

1.206

1.117–1.303

0.000

0.0

0.583

Dominant

1.219

1.123–1.323

0.000

0.0

0.484

Recessive

1.336

0.922–1.936

0.125

0.0

0.939

Codominance AA vs. GG

1.384

0.955–2.006

0.086

0.0

0.932

Codominance GA vs. GG

0.008

0.004–0.017

0.000

83.6

0.000

Complete overdominance

0.827

0.761–0.899

0.000

0.0

0.434

Caucasian

Allele contrast

1.121

1.060–1.186

0.000

0.0

0.964

Dominant

1.127

1.047–1.213

0.001

0.0

0.919

Recessive

1.203

1.067–1.357

0.003

0.0

0.987

Codominance AA vs. GG

1.284

1.131–1.456

0.000

0.0

0.893

Codominance GA vs. GG

0.279

0.132–0.587

0.001

98.0

0.000

Complete overdominance

0.959

0.891–1.033

0.272

0.0

0.457

  1. Notes: I2 represents the variation in OR attributable to heterogeneity. Ph represents the P-value of the Q-test for heterogeneity Abbreviations:CI confidence interval; OR odds ratio