Genetic model
|
OR
|
95% CI
|
P-value
|
I2(%)
|
Ph
|
Combination method
|
---|
Rs1006737
|
Allele contrast
|
1.151
|
1.100–1.204
|
0.000
|
0.0
|
0.867
|
Fixed effects model
|
Dominant
|
1.169
|
1.107–1.234
|
0.000
|
0.0
|
0.786
|
Fixed effects model
|
Recessive
|
1.215
|
1.085–1.360
|
0.001
|
0.0
|
0.999
|
Fixed effects model
|
Codominance AA vs. GG
|
1.296
|
1.151–1.459
|
0.000
|
0.0
|
0.993
|
Fixed effects model
|
Codominance GA vs. GG
|
0.064
|
0.024–0.169
|
0.000
|
99.0
|
0.000
|
Random effects model
|
Complete overdominance
|
0.897
|
0.849–0.948
|
0.000
|
26.1
|
0.173
|
Fixed effects model
|
Rs2007044
|
Allele contrast
|
1.080
|
1.023–1.139
|
0.006
|
0.0
|
0.785
|
Fixed effects model
|
Rs4765905
|
Allele contrast
|
1.225
|
1.100–1.364
|
0.000
|
0.0
|
0.719
|
Fixed effects model
|
- Notes: I2 represents the variation in OR attributable to heterogeneity. Ph represents the P-value of the Q-test for heterogeneity
- Abbreviations:CI confidence interval; OR odds ratio