Table 3 The main results of the overall meta-analysis of CACNA1C polymorphisms
Genetic model | OR | 95% CI | P-value | I2(%) | Ph | Combination method |
|---|---|---|---|---|---|---|
Rs1006737 | ||||||
Allele contrast | 1.151 | 1.100–1.204 | 0.000 | 0.0 | 0.867 | Fixed effects model |
Dominant | 1.169 | 1.107–1.234 | 0.000 | 0.0 | 0.786 | Fixed effects model |
Recessive | 1.215 | 1.085–1.360 | 0.001 | 0.0 | 0.999 | Fixed effects model |
Codominance AA vs. GG | 1.296 | 1.151–1.459 | 0.000 | 0.0 | 0.993 | Fixed effects model |
Codominance GA vs. GG | 0.064 | 0.024–0.169 | 0.000 | 99.0 | 0.000 | Random effects model |
Complete overdominance | 0.897 | 0.849–0.948 | 0.000 | 26.1 | 0.173 | Fixed effects model |
Rs2007044 | ||||||
Allele contrast | 1.080 | 1.023–1.139 | 0.006 | 0.0 | 0.785 | Fixed effects model |
Rs4765905 | ||||||
Allele contrast | 1.225 | 1.100–1.364 | 0.000 | 0.0 | 0.719 | Fixed effects model |