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Table 3 The main results of the overall meta-analysis of CACNA1C polymorphisms

From: The genome-wide supported CACNA1C gene polymorphisms and the risk of schizophrenia: an updated meta-analysis

Genetic model OR 95% CI P-value I2(%) Ph Combination method
Rs1006737
Allele contrast 1.151 1.100–1.204 0.000 0.0 0.867 Fixed effects model
Dominant 1.169 1.107–1.234 0.000 0.0 0.786 Fixed effects model
Recessive 1.215 1.085–1.360 0.001 0.0 0.999 Fixed effects model
Codominance AA vs. GG 1.296 1.151–1.459 0.000 0.0 0.993 Fixed effects model
Codominance GA vs. GG 0.064 0.024–0.169 0.000 99.0 0.000 Random effects model
Complete overdominance 0.897 0.849–0.948 0.000 26.1 0.173 Fixed effects model
Rs2007044
Allele contrast 1.080 1.023–1.139 0.006 0.0 0.785 Fixed effects model
Rs4765905
Allele contrast 1.225 1.100–1.364 0.000 0.0 0.719 Fixed effects model
  1. Notes: I2 represents the variation in OR attributable to heterogeneity. Ph represents the P-value of the Q-test for heterogeneity
  2. Abbreviations:CI confidence interval; OR odds ratio
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BMC Medical Genetics

ISSN: 1471-2350

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