Table 2 The distributions of the allele frequency and genotype in the included studies
Author | Year | Genotype distribution | PHWE | Allele frequency | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
ss | Cases, n | Controls, n | Cases (%) | Control (%) | ||||||||
AA | Aa | aa | AA | Aa | aa | A | a | A | a | |||
Rs1006737 | ||||||||||||
Lubeiro | 2018 | 25 | 23 | 2 | 58 | 38 | 5 | 0.70 | 73 (73.0) | 27 (27.0) | 154 (76.2) | 48 (23.8) |
Fatima | 2017 | 393 | 84 | 17 | 235 | 54 | 9 | 0.01 | 870 (88.1) | 118 (11.9) | 524 (88.0) | 72 (12.0) |
Ivorra | 2014 | 1417 | 1271 | 293 | 1420 | 1124 | 240 | 0.41 | 4105 (68.9) | 1857 (31.1) | 3964 (71.2) | 1604 (28.8) |
Galaktionova | 2013 | 78 | 85 | 23 | 80 | 90 | 22 | 0.66 | 241 (64.8) | 131 (35.2) | 250 (65.1) | 134 (34.9) |
Nyegaard | 2010 | 402 | 444 | 130 | 656 | 675 | 158 | 0.42 | 1248 (63.9) | 704 (36.1) | 1987 (66.7) | 991 (33.3) |
Bigos | 2010 | 120 | 115 | 47 | 191 | 205 | 44 | 0.31 | 355 (62.9) | 209 (37.1) | 587 (66.7) | 293 (33.3) |
Green | 2009 | 205 | 208 | 66 | 1367 | 1233 | 336 | 0.02 | 618 (64.5) | 340 (35.5) | 3967 (67.6) | 1095 (32.4) |
Mallas | 2016 | 23 | 30 | 10 | 56 | 51 | 17 | 0.33 | 76 (60.3) | 50 (39.7) | 163 (65.7) | 85 (34.3) |
Porcelli | 2015 | 153 | 23 | 0 | 301 | 23 | 2 | 0.11 | 329 (93.5) | 23 (6.5) | 625 (95.9) | 27 (4.1) |
He | 2013 | 996 | 220 | 14 | 1053 | 166 | 9 | 0.39 | 2212 (89.9) | 248 (10.1) | 2272 (92.5) | 184 (7.5) |
Guan | 2013 | 1061 | 343 | 26 | 1223 | 327 | 20 | 0.72 | 2465 (86.2) | 395 (13.8) | 2773 (88.3) | 367 (11.7) |
Zheng | 2013 | 5239 | 635 | 19 | 5706 | 597 | 16 | 0.93 | 11,113 (94.3) | 673 (5.7) | 12,009 (95.0) | 629 (5.0) |
Hori | 2012 | 480 | 70 | 2 | 1002 | 127 | 3 | 0.63 | 1030 (93.3) | 74 (6.7) | 2131 (94.1) | 133 (5.9) |
Zhang | 2011 | 280 | 37 | 1 | 357 | 42 | 2 | 0.53 | 597 (93.9) | 39 (6.1) | 756 (94.3) | 46 (5.7) |
Rs2007044 | ||||||||||||
Zhang | 2018 | 24 | 25 | 4 | 58 | 57 | 14 | 1.00 | 73 (68.9) | 33 (31.1) | 173 (67.1) | 85 (32.9) |
Bustillo | 2017 | 26 | 23 | 9 | 35 | 21 | 11 | 0.02 | 75 (64.7) | 41 (35.3) | 91 (67.9) | 43 (32.1) |
Zheng | 2014 | 2797 | 2540 | 559 | 3166 | 2597 | 559 | 0.42 | 8134 (77.5) | 3658 (22.5) | 8929 (70.7) | 3715 (29.3) |
Rs4765905 | ||||||||||||
Sudesh | 2018 | 579 | 307 | 51 | 668 | 286 | 38 | 0.29 | 1465 (78.2) | 409 (21.8) | 1622 (81.8) | 362 (18.2) |
Guan | 2013 | 1307 | 360 | 33 | 1195 | 352 | 24 | 0.74 | 2434 (71.6) | 426 (28.4) | 2741 (87.2) | 399 (12.8) |