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Table 2 The frequencies of IL-2 haplotypes in IVDD patients and healthy controls

From: Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian population

Cytokine Haplotype* IVDD
N (%)
Control (N = 140)
N (%)
P-Value OR 95% CI
IL-2 GG 48 (32.2) 107(38.8) 0.20 0.75 0.49–1.14
TG 65 (43.6) 112(40.6) 0.60 1.13 0.76–1.69
TT 15 (10.1) 56(20.3) 0.009 0.44 0.24–0.81
GT 20 (13.4) 1(0.3)
  1. *Reference: The IL2 haplotype was comprised of -330 T/G SNP (rs2069762), and + 166G/T SNP (rs2069763)