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Table 2 The frequencies of IL-2 haplotypes in IVDD patients and healthy controls

From: Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian population

Cytokine

Haplotype*

IVDD

N (%)

Control (N = 140)

N (%)

P-Value

OR

95% CI

IL-2

GG

48 (32.2)

107(38.8)

0.20

0.75

0.49–1.14

TG

65 (43.6)

112(40.6)

0.60

1.13

0.76–1.69

TT

15 (10.1)

56(20.3)

0.009

0.44

0.24–0.81

GT

20 (13.4)

1(0.3)

  1. *Reference: The IL2 haplotype was comprised of -330 T/G SNP (rs2069762), and + 166G/T SNP (rs2069763)