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Fig. 2 | BMC Medical Genetics

Fig. 2

From: A case of Turcot’s syndrome type 1 with loss of immunoexpression of MSH6 in colon cancer and liver metastasis due to secondary somatic mutation in coding mononucleotide (C)8 tract: a case report

Fig. 2

Histological examination and immunohistochemical staining for mismatch repair proteins of this patient’s tumors. HE staining of a colon tumor revealed a poorly differentiated adenocarcinoma with an increased intratumoral lymphocytes and neutrophils. By immunohistochemistry, the tumor is negative for MLH1 and PMS2 . This tumor has intact expression of MSH2. These glands show scanty staining for MSH6. HE staining of a stomach tumor revealed a moderately differentiated adenocarcinoma

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BMC Medical Genetics

ISSN: 1471-2350

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