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Table 5 Associations between mRNA expression and copy number of IL17RA with clinical features of AS

From: Copy number variation of IL17RA gene and its association with the ankylosing spondylitis risk in Iranian patients: a case-control study

AS patients (N = 68)
Clinical features ESR, mm/h
24 ± 22.09
Disease duration, years
9.47 ± 9.72
BASDAI
score
5.20 ± 2.61
BASFI
score
3.76 ± 2.43
BASMI
score
3.43 ± 1.69
ASQol
score
8.29 ± 5.36
IL17RA
mRNA expression r 0.026 0.015 −0.032 0.111 0.133 0.045
P 0.78 0.91 0.81 0.40 0.34 0.74
Copy number r −0.102 −0.016 0.174 0.134 0.248 0.112
P 0.28 0.90 0.18 0.30 0.07 0.40
mRNA expression β (SE) 0.08 (0.06) 0.23 (0.19) −0.84 (0.69) 1.19 (0.83) −1.2 (0.85) −0.17 (0.34)
P 0.19 0.25 0.23 0.16 0.17 0.62
  1. BASFI bath ankylosing spondylitis functional index, BASDAI bath ankylosing spondylitis disease activity index, BASMI bath ankylosing spondylitis metrology index, ASQOL ankylosing spondylitis quality of life, P Adjusted P-value by Benjamini and Hochberg method to control false discovery rate in multiple testing, SE standard error of coefficient (β), r: Spearman’s correlation coefficient