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Table 5 Associations between mRNA expression and copy number of IL17RA with clinical features of AS

From: Copy number variation of IL17RA gene and its association with the ankylosing spondylitis risk in Iranian patients: a case-control study

AS patients (N = 68)

Clinical features

ESR, mm/h

24 ± 22.09

Disease duration, years

9.47 ± 9.72

BASDAI

score

5.20 ± 2.61

BASFI

score

3.76 ± 2.43

BASMI

score

3.43 ± 1.69

ASQol

score

8.29 ± 5.36

IL17RA

mRNA expression

r

0.026

0.015

−0.032

0.111

0.133

0.045

P

0.78

0.91

0.81

0.40

0.34

0.74

Copy number

r

−0.102

−0.016

0.174

0.134

0.248

0.112

P

0.28

0.90

0.18

0.30

0.07

0.40

mRNA expression

β (SE)

0.08 (0.06)

0.23 (0.19)

−0.84 (0.69)

1.19 (0.83)

−1.2 (0.85)

−0.17 (0.34)

P

0.19

0.25

0.23

0.16

0.17

0.62

  1. BASFI bath ankylosing spondylitis functional index, BASDAI bath ankylosing spondylitis disease activity index, BASMI bath ankylosing spondylitis metrology index, ASQOL ankylosing spondylitis quality of life, P Adjusted P-value by Benjamini and Hochberg method to control false discovery rate in multiple testing, SE standard error of coefficient (β), r: Spearman’s correlation coefficient
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BMC Medical Genetics

ISSN: 1471-2350

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