Table 5 Association analysis of rs1043784 variant in BMP6 in cases and controls according to glaucoma types
Group | Genetic Model | Genotype | Control n (%) | Cases n (%) | OR (95% CI) | p | AIC | BIC | p§ |
|---|---|---|---|---|---|---|---|---|---|
PACG | Co-dominant | T/T | 184 (73.6) | 71 (69.6) | 1.00 | 0.75 | 429.2 | 440.8 | 0.73 |
C/T | 57 (22.8) | 27 (26.5) | 1.23 (0.72–2.09) | ||||||
C/C | 9 (3.6) | 4 (3.9) | 1.15 (0.34–3.86) | ||||||
Dominant | T/T | 184 (73.6) | 71 (69.6) | 1.00 | 0.45 | 427.2 | 434.9 | 0.66 | |
C/T-C/C | 66 (26.4) | 31 (30.4) | 1.22 (0.73–2.02) | ||||||
Recessive | T/T-C/T | 241 (96.4) | 98 (96.1) | 1.00 | 0.89 | 427.8 | 435.5 | 0.63 | |
C/C | 9 (3.6) | 4 (3.9) | 1.09 (0.33–3.63) | ||||||
Over-dominant | T/T-C/C | 193 (77.2) | 75 (73.5) | 1.00 | 0.47 | 427.2 | 435 | 0.5 | |
C/T | 57 (22.8) | 27 (26.5) | 1.22 (0.72–2.07) | ||||||
Log-additive | – | – | – | 1.16 (0.76–1.76) | 0.5 | 427.3 | 435 | 0.85 | |
PXG | Co-dominant | T/T | 184 (73.6) | 64 (67.4) | 1.00 | 0.29 | 409.6 | 421.1 | 0.24 |
C/T | 57 (22.8) | 29 (30.5) | 1.46 (0.86–2.48) | ||||||
C/C | 9 (3.6) | 2 (2.1) | 0.64 (0.13–3.04) | ||||||
Dominant | T/T | 184 (73.6) | 64 (67.4) | 1.00 | 0.25 | 408.8 | 416.5 | 0.24 | |
C/T-C/C | 66 (26.4) | 31 (32.6) | 1.35 (0.81–2.26) | ||||||
Recessive | T/T-C/T | 241 (96.4) | 93 (97.9) | 1.00 | 0.46 | 409.5 | 417.2 | 0.38 | |
C/C | 9 (3.6) | 2 (2.1) | 0.58 (0.12–2.72) | ||||||
Over-dominant | T/T-C/C | 193 (77.2) | 66 (69.5) | 1.00 | 0.14 | 407.9 | 415.6 | 0.13 | |
C/T | 57 (22.8) | 29 (30.5) | 1.49 (0.88–2.52) | ||||||
Log-additive | – | – | – | 1.18 (0.76–1.83) | 0.46 | 409.5 | 417.2 | 0.45 |