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Table 2 Association of genetic models of PIN3 16-bp duplication polymorphism of TP53 with breast cancer risk

From: Association of PIN3 16-bp duplication polymorphism of TP53 with breast cancer risk in Mali and a meta-analysis

Genotype/Allele Cases Controls OR (95% CI) P
N = 60 N = 60
A1A1 27 (45.0) 39 (65.0) Reference  
A1A2 25 (41.7) 16 (26.7) 2.25 (1.01–5.01) 0.04
A2A2 8 (13.3) 5 (8.3) 2.31 (0.68–7.83) 0.17
A2A2 + A1A2 33 (55.0) 21 (35.0) 2.26 (1.08–4.73) 0.02
A1A1 + A1A2 52 (86.7) 55 (91.7) Reference  
A2A2 8 (13.3) 5 (8.3) 1.69 (0.52–5.50) 0.38
A1 79 (65.8) 94 (78.3) Reference  
A2 41 (34.2) 26 (21.7) 1.87 (1.05–3.33) 0.03
  1. N Number, CI confidence Interval, P p-value, A2A2 + A1A2 vs. A1A1: Dominant model, A2A2 vs. A1A1 + A1A2: Recessive model; A2 vs. A1: Additive model.