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Table 3 Joint-effects analysis of the prognostic value of combinations of GSTM1 and GSTM2

From: Clinical significance and biological mechanisms of glutathione S-transferase mu gene family in colon adenocarcinoma

Group

Patients

(n = 438)

No. of events (%)

MST

(days)

Crude

P

Crude HR

(95% CI)

Adjusted

P*

Adjusted HR*

(95% CI)

1

134

24 (17.9%)

2821

0.001

0.421 (0.254–0.697)

0.001

0.416 (0.251–0.689)

2

170

32 (12.4%)

N/A

0.001

0.467 (0.293–0.744)

0.001

0.469 (0.294–0.689)

3

134

42 (31.3%)

1711

< 0.001

Ref.

< 0.001

Ref.

  1. Notes: *, adjustment for tumor stage
  2. Abbreviations: GSTM, Glutathione S-transferase Mu; MST, median survival time; HR, hazard ratio; CI, confidence interval