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Table 3 Joint-effects analysis of the prognostic value of combinations of GSTM1 and GSTM2

From: Clinical significance and biological mechanisms of glutathione S-transferase mu gene family in colon adenocarcinoma

Group Patients
(n = 438)
No. of events (%) MST
(days)
Crude
P
Crude HR
(95% CI)
Adjusted
P*
Adjusted HR*
(95% CI)
1 134 24 (17.9%) 2821 0.001 0.421 (0.254–0.697) 0.001 0.416 (0.251–0.689)
2 170 32 (12.4%) N/A 0.001 0.467 (0.293–0.744) 0.001 0.469 (0.294–0.689)
3 134 42 (31.3%) 1711 < 0.001 Ref. < 0.001 Ref.
  1. Notes: *, adjustment for tumor stage
  2. Abbreviations: GSTM, Glutathione S-transferase Mu; MST, median survival time; HR, hazard ratio; CI, confidence interval