Genetic variation in toll like receptors 2, 7, 9 and interleukin-6 is associated with cytomegalovirus infection in late pregnancy

Table 4 Comparison of variant allele frequencies of genotyped SNPs with other populations

Gene	SNP	Variant allele	Zimbabwean (This study)	Other Africans	Europeans	Asians
TLR2	rs4696480	A	0.31	0.37	0.52	0.57
TLR2	rs3804099	T	0.45	0.36	0.56	0.72
TLR2	rs1816702	T	0.47	0.43	0.12	0.00
TLR4	rs1554973	T	0.20	0.21	0.77	0.86
TLR4	rs2737190	A	0.14	0.16	0.33	0.37
TLR4	rs10759932	C	0.19	0.25	0.85	0.76
TLR4	rs7856729	T	0.38	0.33	0.13	0.10
TLR7	rs179008	T	0.23	0.12	0.23	0.00
TLR9	rs352139	C	0.42	0.61	0.55	0.40
TLR9	rs5743836	G	0.36	0.42	0.13	0.00
TLR9	rs187084	G	0.30	0.29	0.43	0.40
TLR9	rs352140	T	0.32	0.29	0.55	0.39
IL-6	rs10499563	C	0.31	0.27	0.23	0.16
IL-6R	rs4537545	C	0.26	0.34	0.37	0.32
IL-10	rs1800872	T	0.40	0.44	0.24	0.68
IL-10	rs1878672	C	0.25	0.26	0.45	0.05
IL-28B	rs12979860	G	0.70	0.82	0.86	0.97
IFNAR1	rs2843710	G	0.30	0.31	0.41	0.36
IFNAR1	rs113181057	C	0.00	N/A	N/A	N/A
IL-1A	rs1800587	C	0.65	0.60	0.71	0.93

Key: SNP Single nucleotide polymorphism, TLR Toll-like receptor, IL Interleukin, IFNAR Interferon α

ISSN: 1471-2350