Table 3 Multivariable adjusted models containing BMI and significant SNPs in univariable analysis for CMV status
SNP | Model | Genotype | OR (95%CI) | p-value |
|---|---|---|---|---|
TLR2 rs1816702 | Codominant | C/T | 0.09 (0.02–0.43) | 0.001 |
T/T | 0.06 (0.01–0.48) |  | ||
Dominant | C/T-T/T | 0.08 (0.02–0.37) | 0.0003 | |
Recessive | T/T | 0.32 (90.07–1.50) | 0.133 | |
Overdominant | C/T | 0.29 (0.08–1.01) | 0.044 | |
Log additive | 0,1,2 | 0.22 (0.08–0.62) | 0.001 | |
TLR7 rs179008 | Codominant | A/T | 3.67 (0.79–116.99) | 0.011 |
T/T | 18.69 (1.59–220.04) |  | ||
Dominant | A/T-T/T | 6.05 (1.53–23.94) | 0.006 | |
Recessive | T/T | 13.15 (1.15–149.74) | 0.013 | |
Overdominant | A/T | 2.27 (0.53–9.68) | 0.262 | |
Log additive | 0,1,2 | 4.08 (1.46–11.39) | 0.003 | |
TLR9 rs352139 | Codominant | T/C | 2.87 (0.50–16.58) | 0.144 |
C/C | 8.13 (0.90–73.63) |  | ||
Dominant | T/C-C/C | 3.58 (0.65–19.66) | 0.121 | |
Recessive | C/C | 3.65 (0.67–19.77) | 0.124 | |
Overdominant | T/C | 1.05 (0.30–3.68) | 0.938 | |
Log additive | 0,1,2 | 2.85 (0.95–8.58) | 0.049 | |
Il-6 rs10499563 | Codominant | T/C | 0.05 (0.01–0.25) | < 0.001 |
C/C | 0.42 (0.05–3.77) |  | ||
Dominant | T/C-C/C | 0.08 (0.02–0.31) | < 0.001 | |
Recessive | C/C | 1.53 (0.21–11.39) | 0.682 | |
Overdominant | T/C | 0.06 (0.01–0.27) | < 0.001 | |
Log additive | 0,1,2 | 0.19 (0.06–0.58) | 0.001 |