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Table 1 Frequency distribution of VEGF genotypes in different histopathological types of lung cancer

From: Correlation of gene polymorphisms of vascular endothelial growth factor with grade and prognosis of lung cancer

Variables

Squamous cell carcinoma

Adenocarcinoma

Adenoacanthoma

Others

P value

(n = 158)

(n = 215)

(n = 30)

(n = 55)

−2578C > A (%)

    

0.964

 AA

10 (6.33)

11 (5.12)

1 (3.33)

2 (3.64)

 

 AC

65 (41.14)

82 (38.14)

12 (40.00)

23 (41.82)

 

 CC

83 (52.53)

122 (56.74)

17 (56.67)

30 (54.55)

 

−1154G > A (%)

    

0.814

 AA

5 (3.16)

4 (1.86)

0 (0.00)

1 (1.82)

 

 AG

50 (31.65)

56 (26.05)

8 (26.67)

17 (30.91)

 

 GG

103 (65.19)

155 (72.09)

22 (73.33)

37 (67.27)

 

−460 T > C (%)

    

0.969

 CC

0 (6.33)

12 (5.58)

1 (3.33)

2 (3.64)

 

 CT

65 (41.14)

82 (38.14)

12 (40.00)

23 (41.82)

 

 TT

83 (52.53)

121 (56.28)

17 (56.67)

30 (54.55)

 

+405G > C (%)

    

0.990

 CC

29 (18.35)

42 (19.53)

7 (23.33)

9 (16.36)

 

 CG

81 (51.27)

108 (50.23)

14 (46.67)

30 (54.55)

 

 GG

48 (30.38)

65 (30.23)

9 (30.00)

16 (29.09)