Skip to main content

Table 1 Characteristics of included studies in the meta-analysis

From: Association between IL28B Polymorphisms and Outcomes of Hepatitis B Virus Infection: A meta-analysis

Author Years/countries Ethnicity Sources SNPs Genotypes Sample size HWE in control NOS score
Healthy control HBV recovery HBV persistence
Martin MP [20] 2010/United States Caucasian Hospital-based rs12979860 CC/CT/TT
T vs C
157/175/52
279 vs 489
99/94/33
160 vs 292
0.77 7
L.J.Peng [21] 2011/China Asian Population-based rs12979860 CC/CT + TT 206/22 574/77 > 0.05 8
Li WY [22] 2011/China Asian Hospital-based rs12979860 CC/CT + TT 179/24 180/23 178/25 > 0.05 8
rs12980275 AA/AG + GG 178 vs 25 181/22 179/24 > 0.05  
rs8099917 TT/GT + GG 182/21 182/21 180/23 > 0.05  
Fabris C [23] 2011/Italy Caucasian Population-based rs12979860 CC/CT/TT
T vs C
164/145/35
215 vs 473
36/35/4
43 vs 107
0.386 8
Chen J [24] 2012/China Asian Population-based rs12979860 CC/CT/TT
T vs C
213/29/2
33 vs 455
1043/152/10
172 vs 2238
0.37 8
rs12980275 AA/AG/GG
G vs A
210/33/1
35 vs 453
1036/162/8
178 vs 2234
> 0.05  
rs8099917 GG/GT/TT
G vs T
218/25/1
27 vs 461
1075/126/4
130 vs 2276
> 0.05  
Ren S [19] 2012/China Asian Hospital-based rs12979860 CC/CT/TT
T vs C
43/4/0
4 vs 90
33/7/3
13 vs 73
177/46/16
78 vs 400
0.01 8
rs12980275 AA/AG/GG
G vs A
43/3/1
5 vs 89
37/5/1
7 vs 79
205/30/4
38 vs 440
0.01  
rs8099917 GG/GT/TT
G vs T
44/2/1
4 vs 90
33/6/4
14 vs 72
197/31/11
53 vs 425
0.07  
Luz MC [25] 2012/Spain Caucasian Hospital-based rs12979860 CC/CT/TT
T vs C
22/21/6
33 vs 65
29/17/3
23 vs 75
0.78 7
Lee DH [26] 2013/South Korea Asian Hospital-based rs12979860 T vs C 24 vs 380 62 vs 973 > 0.05 7
rs12980275 G vs A 27 vs 377 70 vs 965 > 0.05  
rs8099917 G vs T 22 vs 382 56 vs 979 > 0.05  
Al-Qahtani [27] 2013/Saudi Arabia Caucasian Hospital-based rs12979860 CC/CT/TT
T vs C
174/91/20
131 vs 439
450/274/92
458 vs 1174
> 0.05 7
rs12980275 AA/AG/GG
G vs A
175/93/36
165 vs 443
548/229/44
317 vs 1325
> 0.05  
rs8099917 GG/GT/TT
G vs T
15/73/216
103 vs 505
31/187/606
249 vs 1399
> 0.05  
Kim SU [13] 2013/South Korea Asian Hospital-based rs12979860 CC/CT/TT
T vs C
85/15/0
15 vs 185
189/31/0
31 vs 409
144/10/0
10 vs 298
> 0.05 7
rs12980275 AA/AG/GG
G vs A
90/16/0
16 vs 196
208/34/1
36 vs 450
185/18/0
18 vs 388
> 0.05  
rs8099917 GG/GT/TT
G vs T
90/16/0
16 vs 196
215/26/0
26 vs 456
192/12/0
12 vs 396
> 0.05  
Seto WK [28] 2013/China Asian Hospital-based rs12979860 T vs C 11 vs 192 14 vs 189 > 0.05 7
rs8099917 G vs T 13 vs 190 15 vs 188 > 0.05  
Senem CK [29] 2014/Turkey Caucasian Population-based rs12979860 CC/CT/TT
T vs C
46/65/6
77 vs 157
215/201/57
315 vs 631
> 0.05 7
rs12980275 AA/AG/GG
G vs A
36/67/15
97 vs 139
191/207/58
323 vs 589
> 0.05  
Akkiz H [30] 2014/Turkey Caucasian Hospital-based rs12979860 CC/CT/TT
T vs C
92/91/25
141 vs 275
43/50/17
84 vs 136
0.30 7
Liao Y [31] 2014/ China Asian Hospital-based rs12979860 CC/CT + TT
T vs C
420/66
66 vs 906
391/66
70 vs 844
> 0.05 8
rs12980275 AA/AG + GG
G vs A
418/68
68 vs 904
388/69
77 vs 842
> 0.05  
rs8099917 GG/GT + TT
G vs T
470/16
16 vs 956
433/24
24 vs 890
> 0.05  
Shi XD [32] 2015/China Asian Population-based rs12979860 CC/CT/TT
T vs C
19/0/0
0 vs 38
114/23/0
23 vs 251
> 0.05 7
Kimkong [33] 2015/Thailand Asian Hospital-based rs12979860 CC/CT/TT
T vs C
140/24/0
24 vs 304
116/12/0
12 vs 244
> 0.05 7
rs8099917 GG/GT/TT
G vs T
0/25/139
25 vs 303
0/8/120
8 vs 248
> 0.05  
Song YZ [14] 2017/China Asian Hospital-based rs12979860 CC/CT/TT
T vs C
400/57/3
63 vs 857
439/52/2
56 vs 930
0.79 7
rs12980275 AA/AG/GG
G vs A
398/58/4
66 vs 854
437/55/1
57 vs 929
0.50  
rs8099917 GG/GT/TT
G vs T
2/52/406
56 vs 864
1/49/443
51 vs 935
> 0.05  
Baghbani JM [34] 2017/Iran Caucasian Hospital-based rs12979860 CC/CT/TT
T vs C
28/49/17
83 vs 105
31/44/8
60 vs 106
> 0.05 7
rs8099917 GG/GT/TT
G vs T
9/32/53
50 vs 138
4/17/62
25 vs 141
> 0.05