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Table 1 Biochemical parameters of the two patients before and after treatment

From: Novel PYGL mutations in Chinese children leading to glycogen storage disease type VI: two case reports

 

Patient 1

Patient 2

Reference

Before

Aftera

Before

Afterb

Glucose (mmol/L)

4.26

4.23

3.43

4.2

3.8–6.2

ALT (U/L)

162.8

30

92

11

10–40

AST (U/L)

230.9

38

102

28

10–40

γGT(U/L)

61

10

74

11

0–25

Lactate (mmol/L)

4.03/2.5c

1.0

NA

1.3

0.7–2.1

TG (mmol/L)

4.39

2.15

4.37

1.57

0.56–1.69

TC (mmol/L)

3.47

3.09

3.7

3.76

2.33–5.69

Uric acid (μmol/L)

342

208

402

322

100–410

Total protein (g/L)

58.2

60.1

66.4

70.7

58–80

Prealbumin (mg/L)

180

NA

160

NA

100–300

Ketone (mmol/L)d

N

N

N

N

N

CK

22

NA

51

NA

18–173

  1. Abbreviations: ALT alanine transaminase, AST aspartate aminotransferase, γGT gamma-glutamyl transpeptidase, TG triglycerides, TC total cholesterol, N negative, NA not available
  2. aThe laboratory values of patient 1 after treatment for 8 months
  3. bThe laboratory values of patient 2 after treatment for 13 months
  4. cThe lactate concentration had been tested for twice after fasting
  5. dKetone test used urine sample, and the other biochemical tests used serum samples