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Table 1 Detailed evaluation criteria focused on included studies

From: Association between the IL-10 and IL-6 polymorphisms and brucellosis susceptibility: a meta-analysis

Criterion of evaluation

score

Reliability of controls

 Live in the area locally

3

 Volunteers who conduct blood or organ transplant

2

 Patients who is not related with Brucellosis

1

 Not reported or cannot get the detailed information

0

Matching standard

 All including age, sex and ethnicity

3

 Ethnicity only

1.5

 Not reported or cannot get the detailed information

0

Diagnosis of Brucellosis

 According to clinical manifestation and high antibodies

3

 According to history or other examination

1.5

 Not reported or cannot get the detailed information

0

Genotyping methods

 by “blinded” status

3

 Not reported or cannot get the detailed information

0

Hardy-Weinberg equilibrium

 The compliance is good

3

 Not reported or cannot get the detailed information

0

Sample size

 More than 500

3

 More than 200 and less than or equal to 500

2

 More than 100 and less than or equal to 200

1

 less than 100

0