Table 2 Analysis of psoriasis susceptibility related to angiotensin-converting enzyme insertion/deletion (I/D) polymorphism based on the studies with normal Hardy–Weinberg Equilibrium when considering controls, ethnicity, psoriasis subtype, controls source, Caucasian population

Overall (16)

0.96 (0.82, 1.12), 74, < 0.00001

0.99 (0.73, 1.36), 71, < 0.00001

0.81 (0.72, 0.91), 42, 0.04

0.91 (0.73, 1.13), 64, 0.0003

1.05 (0.85, 1.30), 61, 0.0007

 East Asian (4)

0.95 (0.68, 1.32),86, < 0.0001

0.99 (0.51, 1.93), 84, 0.0004

0.82 (0.61, 1.10), 63, 0.05

0.86 (0.59, 1.25), 79, 0.003

1.09 (0.65, 1.84), 77, 0.005

 Caucasian (12)

0.96 (0.79, 1.17), 70, 0.0001

0.99 (0.68, 1.45), 67, 0.0005

0.82 (0.69, 0.97), 39, 0.08

0.95 (0.71, 1.27), 59, 0.004

1.03 (0.81, 1.32), 57, 0.007

 Arthritis (4)

0.83 (0.61, 1.12), 66, 0.03

0.69 (0.52, 0.91), 49, 0.12

0.66 (0.50, 0.85), 0, 0.78

0.67 (0.52, 0.86), 8, 0.35

1.04 (0.73, 1.48), 53, 0.09

 Vulgaris (5)

1.12 (0.77, 1.65), 65, 0.02

1.29 (0.62, 2.68), 63, 0.03

1.19 (0.65, 2.21), 60, 0.04

1.29 (0.64, 2.63), 71, 0.009

1.02 (0.76, 1.37), 0, 0.48

 Hospital-based (9)

0.84 (0.68, 1.04),72, 0.0004

0.84 (0.55, 1.29), 68, 0.002

0.77 (0.67, 0.90), 23, 0.24

0.80 (0.61, 1.04), 56, 0.02

0.97 (0.71, 1.32), 58, 0.01

 Others (7)

1.12 (0.88, 1.42), 77, 0.0003

1.22 (0.74, 2.01), 77, 0.0002

1.00 (0.72, 1.40), 59, 0.02

1.11 (0.75, 1.64), 72, 0.001

1.14 (0.83, 1.56), 68, 0.005

 Arab (4)

1.04 (0.52, 2.06), 75, 0.008

1.65 (0.91, 3.00), 2, 0.38

1.43 (0.81, 2.53), 0, 0.47

1.56 (0.93, 2.62), 7, 0.36

1.41 (0.89, 2.23), 0, 0.68

 Europe (4)

0.94 (0.81, 1.10), 21, 0.28

0.85 (0.62, 1.16), 18, 0.30

0.84 (0.63, 1.12), 47, 0.13

0.84 (0.64, 1.10), 48, 0.13

0.99 (0.79, 1.24), 4, 0.37

 Other (Iran, Pakistan, and Turkey) (4)

0.93 (0.64, 1.34), 85, 0.0001

0.83 (0.38, 1.84), 86, < 0.0001

0.73 (0.58, 0.92), 41, 0.17

0.82 (0.49, 1.36), 75, 0.007

0.97 (0.57, 1.66), 84, 0.0003