Table 5 Correlation analysis of LRCH1 polymorphisms under different genetic models and DEACMP risk
SNPs | Genetic models | DEACMP | ACMP | Pobs | OR(95%CI) | |
|---|---|---|---|---|---|---|
rs1539177 | allele | (G/A) | 263/201 | 530/322 | 0.050346 | 0.795 (0.632–1.001) |
additive | (GG/AG/AA) | 67/129/36 | 162/206/58 | 0.043729 | 1.279 (1.007–1.624) | |
dominant | (GG/AG + AA) | 67/165 | 162/264 | 0.018579 | 1.511 (1.070–2.133) | |
recessive | (GG + AG/AA) | 196/36 | 368/58 | 0.50527 | 1.165 (0.743–1.828) | |
rs17068697 | allele | (G/A) | 205/263 | 416/428 | 0.056602 | 0.802 (0.639–1.006) |
additive | (GG/AG/AA) | 33/139/62 | 95/226/101 | 0.043125 | 1.285 (1.008–1.6381) | |
dominant | (GG/AG + AA) | 33/201 | 95/327 | 0.009228 | 1.770 (1.147–2.729) | |
recessive | (GG + AG/AA) | 172/62 | 321/101 | 0.466963 | 1.146 (0.794–1.653) | |
rs9534475 | allele | (A/C) | 265/205 | 530/322 | 0.038445 | 1.273 (1.013–1.601) |
additive | (AA/AC/CC) | 67/137/37 | 167/196/63 | 0.035878 | 1.285 (1.017–1.623) | |
dominant | (AA/AC + CC) | 67/168 | 167/259 | 0.005935 | 1.617 (1.147–2.280) | |
recessive | (AA+AC/CC) | 198/37 | 363/63 | 0.742672 | 1.077 (0.693–1.674) | |
rs2236592 | allele | (T/C) | 228/242 | 454/394 | 0.080373 | 1.223 (0.976–1.533) |
additive | (TT/TC/CC) | 44/140/51 | 115/224/85 | 0.064827 | 1.254 (0.986–1.597) | |
dominant | (TT/TC + CC) | 44/191 | 115/309 | 0.015784 | 1.616 (1.092–2.390) | |
recessive | (TT + TC/CC) | 184/51 | 339/85 | 0.61508 | 1.105 (0.748–1.634) | |