SNP | Crude | p | Model 1 | p | Model 2 | p | |
---|---|---|---|---|---|---|---|
Cohort A | |||||||
rs7330636 | GG | 1.000 | 1.000 | 1.000 | |||
GA | 0.725 (0.540–0.974) | 0.033 | 0.725 (0.538–0.976) | 0.034 | 0.644 (0.437–0.949) | 0.026 | |
AA | 1.403 (0.271–7.255) | 0.686 | 1.520 (0.292–7.922) | 0.619 | 1.415 (0.206–9.735)) | 0.724 | |
rs9590999 | CC | 1.000 | 1.000 | 1.000 | |||
CT | 0.767 (0.610–0.965) | 0.023 | 0.757 (0.601–0.953) | 0.018 | 0.738 (0.551–0.989) | 0.042 | |
TT | 0.921 (0.700–1.212 | 0.921 | 0.914 (0.692–1.205) | 0.522 | 0.880 (0.624–1.239) | 0.463 | |
rs2183057 | AA | 1.000 | 1.000 | 1.000 | |||
AG | 1.054 (0.856–1.298) | 0.620 | 1.067 (0.856–1.316) | 0.546 | 1.131 (0.865–1.479) | 0.369 | |
GG | 1.500 (1.109–2.030) | 0.009 | 1.500 (1.106–2.034) | 0.009 | 1.448 (0.990–2.118) | 0.056 | |
rs4942595 | TT | 1.000 | 1.000 | 1.000 | |||
TC | 0.757 (0.603–0.952) | 0.017 | 0.748 (0.594–0.941) | 0.013 | 0.739 (0.552–0.989) | 0.042 | |
CC | 0.919 (0.699–1.209) | 0.547 | 0.911 (0.692–1.201) | 0.510 | 0.907 (0.645–1.276) | 0.574 | |
rs4531630 | AA | 1.000 | 1.000 | 1.000 | |||
AG | 0.844 (0.672–1.060) | 0.144 | 0.834 (0.663–1.050) | 0.122 | 0.792 (0.592–1.059) | 0.115 | |
GG | 0.718 (0.544–0.947) | 0.019 | 0.705 (0.533–0.933) | 0.015 | 0.658 (0.462–0.938) | 0.021 | |
rs17069883 | AA | 1.000 | 1.000 | 1.000 | |||
AC | 1.196 (0.955–1.497) | 0.119 | 1.197 (0.954–1.502) | 0.121 | 1.197 (0.896–1.598) | 0.224 | |
CC | 1.426 (1.080–1.882) | 0.012 | 1.449 (1.095–1.916) | 0.009 | 1.447 (1.018–2.056) | 0.040 | |
rs4942578 | CC | 1.000 | 1.000 | 1.000 | |||
CA | 0.991 (0.806–1.220) | 0.935 | 1.007 (0.816–1.241) | 0.950 | 1.054 (0.808–1.376) | 0.696 | |
AA | 1.264 (0.941–1.699) | 0.120 | 1.288 (0.956–1.736) | 0.096 | 1.562 (1.072–2.275) | 0.020 | |
Cohort B | |||||||
rs4942578 | CC | 1.000 | 1.000 | 1.000 | |||
CA | 0.969 (0.871–1.079) | 0.569 | 0.979 (0.876–1.094) | 0.710 | 0.894 (0.759–1.053) | 0.180 | |
AA | 0.926 (0.793–1.081) | 0.328 | 0.949 (0.808–1.114) | 0.521 | 0.735 (0.582–0.929) | 0.010 | |
rs985933 | AA | 1.000 | 1.000 | 1.000 | |||
AG | 0.999 (0.893–1.117) | 0.986 | 1.013 (0.902–1.138) | 0.824 | 1.057 (0.892–1.252) | 0.521 | |
GG | 0.924 (0.799–1.069) | 0.289 | 0.922 (0.793–1.073) | 0.293 | 0.789 (0.631–0.986) | 0.037 | |
rs4941573 | TT | 1.000 | 1.000 | 1.000 | |||
TC | 1.106 (0.979–1.249) | 0.106 | 1.137 (1.001–1.290) | 0.048 | 1.327 (1.101–1.599) | 0.003 | |
CC | 1.021 (0.886–1.176) | 0.774 | 1.033 (0.891–1.196) | 0.670 | 1.113 (0.896–1.383) | 0.332 | |
rs6313 | GG | 1.000 | 1.000 | 1.000 | |||
GA | 1.114 (0.987–1.257) | 0.079 | 1.157 (1.021–1.311) | 0.023 | 1.365 (1.135–1.643) | 0.001 | |
AA | 1.024 (0.889–1.179) | 0.745 | 1.042 (0.899–1.206) | 0.586 | 1.130 (0.911–1.403) | 0.267 | |
rs1328685 | TT | 1.000 | 1.000 | 1.000 | |||
TC | 0.948 (0.817–1.100) | 0.478 | 0.939 (0.805–1.096) | 0.427 | 0.982 (0.786–1.228) | 0.875 | |
CC | 0.570 (0.271–1.199) | 0.138 | 0.544 (0.252–1.175) | 0.121 | 0.292 (0.097–0.883) | 0.029 | |
rs2567675 | TT | 1.000 | 1.000 | 1.000 | |||
TC | 0.898 (0.807–0.999) | 0.047 | 0.868 (0.776–0.969) | 0.012 | 0.832 (0.708–0.979) | 0.027 | |
CC | 0.911 (0.721–1.151) | 0.435 | 0.880 (0.690–1.123) | 0.305 | 0.799 (0.561–1.138) | 0.214 |