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Fig. 4 | BMC Medical Genetics

Fig. 4

From: An analysis of mutational signatures of synonymous mutations across 15 cancer types

Fig. 4

Mutational signatures of synonymous hotspot mutation in 15 cancer typers. a Histogram of the number of hotspot mutations under different sequence contexts. b Bar diagram where the value 100% represents the total number of mutations under different sequence contexts distributed in each cancer type. ATts, AT transition (coral bar in a and b); ATtv, AT transversion (blue bar in a and b); C_GCts, CpG-island GC transition (yellow bar in a and b); C_GCtv, CpG-island GC transversion (rose bar in a and b); NC_GCts, non-CpG-island GC transition (green bar in a and b); NC_GCtv, non-CpG-island GC transversion (grey bar in a and b)

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