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Table 2 Allele and genotype frequencies of SLCO1B1 in patients taking aspirin

From: Increased risk of aspirin-induced gastric mucosal erosion in elderly Chinese men harboring SLCO1B1*1b/*1b while using aspirin and an ACEI or ARB concomitantly

GeneAllele frequencies p† value for HWEControl
n = 250(%)
Case
n = 286 (%)
pGenotypeControl
n = 125 (%)
Case
n = 143 (%)
p
SLCO1B1A = 0.2878 (31.2)74 (25.9)0.172AA9 (7.2)10 (7.0)0.947
388 A > GG = 0.72172 (68.8)212 (74.1) AG60 (48)54 (37.8)0.091
rs2306283P† = 0.44   GG56 (44.8)79 (55.2)0.088
SLCO1B1T = 0.79180 (72.0)245 (85.7)<0.001TT73 (58.4)111 (77.6)0.001
521 T > CC = 0.2170 (28.0)41 (14.3) TC34 (27.2)23 (16.1)0.027
rs4149056P† = 0.37   CC18 (14.4)9 (6.3)0.028
  1. p values from the Chi-squared test. †, Hardy–Weinberg equilibrium (HWE) of allele frequencies at individual loci was assessed by comparing the observed and expected genotype frequencies