Table 1 Demographic and clinical characteristics of the study patients
Variable | Control n = 125 | Case n = 143 | p |
|---|---|---|---|
Age, yrs | 71.5 (9.6) | 78.5 (10.1) | <0.001 |
Body mass index (kg/m2) | 24.5 (2.6) | 25 (2.9) | 0.79 |
SBP (mmHg) | 126.5 (14.7) | 131.3 (14.4) | 0.23 |
DBP (mmHg) | 73.4 (9) | 71.7 (9.9) | 0.13 |
Glucose (mmol/L) | 6.6 (2.3) | 6.9 (2.7) | 0.33 |
TC (mmol/L) | 4.3 (0.9) | 4.2 (0.8) | 0.51 |
LDL-C (mmol/L) | 3.0 (0.9) | 3.1 (0.6) | 0.93 |
APTT (s) | 35.2 (3.8) | 39.6 (2.6) | 0.15 |
Platelet count (109 cells/L) | 261.6 (43.3) | 239.2 (40.5) | 0.08 |
Creatinine (μmol/ L) | 88.3 (45.8) | 96 (35.3) | <0.01 |
eGFR (ml/min/1.73 m2) | 70.9 (18.5) | 55.8 (23.1) | <0.001 |
Alcohol drinking, n (%) | 8 (6.4) | 10 (7.0) | 0.85 |
Smoking, n (%) | 18 (14.4) | 25 (17.5) | 0.49 |
H. pylori-positive, n (%) | 18 (14.4) | 30 (20.9) | 0.16 |
History of gastric ulcers, n (%) | 7 (5.6) | 20 (14) | 0.02 |
Diabetes mellitus, n (%) | 30 (24) | 58 (40.6) | <0.01 |
Hyperlipidemia, n (%) | 58 (46.4) | 68 (47.6) | 0.85 |
Cerebrovascular disease, n (%) | 32 (25.6) | 31 (21.7) | 0.45 |
ARBs or ACEIs, n (%) | 125 (100) | 143 (100) | 1.0 |
Statins, n (%) | 44 (35.2) | 59 (41.3) | 0.31 |
PPIs, n (%) | 63 (50.4) | 26 (18.2) | <0.001 |
NSAIDs, n (%) | 2 (1.6) | 7 (4.9) | 0.18 |