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Table 1 Demographic and clinical characteristics of the study patients

From: Increased risk of aspirin-induced gastric mucosal erosion in elderly Chinese men harboring SLCO1B1*1b/*1b while using aspirin and an ACEI or ARB concomitantly

VariableControl
n = 125
Case
n = 143
p
Age, yrs71.5 (9.6)78.5 (10.1)<0.001
Body mass index (kg/m2)24.5 (2.6)25 (2.9)0.79
SBP (mmHg)126.5 (14.7)131.3 (14.4)0.23
DBP (mmHg)73.4 (9)71.7 (9.9)0.13
Glucose (mmol/L)6.6 (2.3)6.9 (2.7)0.33
TC (mmol/L)4.3 (0.9)4.2 (0.8)0.51
LDL-C (mmol/L)3.0 (0.9)3.1 (0.6)0.93
APTT (s)35.2 (3.8)39.6 (2.6)0.15
Platelet count (109 cells/L)261.6 (43.3)239.2 (40.5)0.08
Creatinine (μmol/ L)88.3 (45.8)96 (35.3)<0.01
eGFR (ml/min/1.73 m2)70.9 (18.5)55.8 (23.1)<0.001
Alcohol drinking, n (%)8 (6.4)10 (7.0)0.85
Smoking, n (%)18 (14.4)25 (17.5)0.49
H. pylori-positive, n (%)18 (14.4)30 (20.9)0.16
History of gastric ulcers, n (%)7 (5.6)20 (14)0.02
Diabetes mellitus, n (%)30 (24)58 (40.6)<0.01
Hyperlipidemia, n (%)58 (46.4)68 (47.6)0.85
Cerebrovascular disease, n (%)32 (25.6)31 (21.7)0.45
ARBs or ACEIs, n (%)125 (100)143 (100)1.0
Statins, n (%)44 (35.2)59 (41.3)0.31
PPIs, n (%)63 (50.4)26 (18.2)<0.001
NSAIDs, n (%)2 (1.6)7 (4.9)0.18
  1. Data are presented as the mean ± SD, or n (%), as appropriate
  2. Abbreviations: ACEIs Angiotensin-converting enzyme inhibitors, APTT Activated partial thromboplastin time, ARBs Angiotensin receptor blockers, DBP Diastolic blood pressure, eGFR Estimated glomerular filtration rate, LDL-C Low-density lipoprotein cholesterol, NSAIDs Nonsteroidal anti-inflammatory drug, PPIs Proton-pump inhibitors, SBP Systolic blood pressure, TC Total cholesterol