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Fig. 2 | BMC Medical Genetics

Fig. 2

From: Novel EIF2AK4 mutations in histologically proven pulmonary capillary hemangiomatosis and hereditary pulmonary arterial hypertension

Fig. 2

Histopathologic findings on open lung biopsy of patient AII.2. The alveolar septa are highly thickened (a). Small and intermediate size veins show thickened walls and narrowed lumens due to concentric laminar fibrosis (a and b respectively). Medium and large arteries have a thickened media and prominent intimal fibrosis (c,d). Symbols: *, intima; arrow, media; arrow head, alveolar septa

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