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Fig. 5 | BMC Medical Genetics

Fig. 5

From: Copy number variation is highly correlated with differential gene expression: a pan-cancer study

Fig. 5

AUGs and DDGs are involved in different parts of cellular dysfunction in tumor. a. Scatter plot shows the KEGG enrichment of AUGs (left) and DDGs (right) by DAVID. The y-axis represents the p value and the x-axis represents the number of enriched genes. b. Kaplan-Meier curves for overall survival (OS) based on variation tendency of FYTTD1 in ESCA, CTTN in HNSC and MTAP in MESO. A&U represents samples with copy number amplification and gene expression upregulation, N-A&U represents samples without copy number amplification and gene expression upregulation; D&D represents samples with copy number deletion and gene expression downregulation, N-D&D represents samples without copy number deletion and gene expression downregulation. c. PPI network of interactive proteins with FYTTD1 by using STRING platform. d. Functional enrichments of the PPI network including GO biological process and KEGG pathways

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