Skip to main content
Fig. 1 | BMC Medical Genetics

Fig. 1

From: Vitamin D receptor ApaI polymorphism associated with progression of liver disease in Vietnamese patients chronically infected with hepatitis B virus

Fig. 1

Illustration of ARMS assay for analyzing VDR polymorphisms. Upper panel: Schematic diagram of the principle of ARMS to detect mutant and wildtype alleles using allele specific primers. Lower panel: Gel electrophoresis analyses to distinguish genotypes of each VDR polymorphism. (i) ApaI polymorphism: AA genotype: 2 bands, 420 and 280 bp; CC genotype: 2 bands, 420 and 180 bp; AC genotype: 3 bands, 420, 280 and 180 bp. (ii) FokI polymorphism: GG genotype: 2 bands, 477 and 360 bp; AA genotype: 2 bands, 477 and 160 bp; GA genotype: 3 bands, 477, 360 and 160 bp. (iii) BsmI polymorphism: TT genotype: 2 bands, 458 and 150 bp; TC genotype: 3 bands, 458, 350 and 150 bp. (iv) TaqI polymorphism: TT genotype: 2 bands, 415 and 300 bp; TC genotype: 3 bands, 415, 300 and 150 bp

Back to article page